Antidepressants may cause problems in patients with bipolar disorder only when they are used in isolation, research suggests. “This is important because treatment options for bipolar depression are urgently needed”, study author Mikael Landén (University of Gothenburg, Sweden) and colleagues reported in the American Journal of Psychiatry.

“[P]atients with bipolar disorder spend most of their time in depressive episodes, and depressive symptoms are the leading cause of impairment and morbidity in bipolar patients.”

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