Music featuring calming noises from nature significantly reduces delirium following coronary artery bypass grafting (CABG), according to study results published in the Journal of Cardiothoracic and Vascular Anesthesia.
Researchers conducted a randomized, single-center trial that comprised patients (N=200) undergoing CABG at the Milad hospital in Iran between 2020 and 2021. Study participants were randomly assigned to receive either the music intervention (n=100; 82% men; mean age, 62.2±7.5 years) or routine care (n=100; 78% men; mean age, 64.7±7.9 years).
The relaxation music was of the new age genre featuring bird, water, and wind sounds accompanied by piano or violin that was played for 1 hour at 2:00 pm and 8:00 pm for 7 days and delivered via headphones at a 10% volume level. Patients were evaluated daily at 3:00 pm and 9:00 pm by the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).
Among the music and control cohorts 16% and 10% had no hypertension, diabetes, and/or hyperlipidemia comorbidities; and 96% and 90% smoked, respectively.
Clinical and surgical variables were well balanced between groups; however, the control group had significantly shorter operations compared with the intervention group (mean, 242.4 vs 261.6 min; P =.03), respectively.
A total of 3 in the intervention cohort and 12 in the control cohort were positive for CAM-ICU (P =.016) during intensive care admission in the first 48 hours following CABG.
No other significant differences were observed.
Limitations of the study include the fact that some patients expressed a lack of interest in the type of music. However, these patients were compliant and listened to the entire hour-long session at all intervention times.
Study authors concluded, “According to these findings, music reduced delirium incidence in post-CABG patients. However, the mean vital signs and venous blood gas parameters may not be influenced. Therefore, this research could demonstrate music efficacy as a practical method for prevention and reducing delirium.”
Esfahanian F, Mirmohammadsadeghi A, Gholami H, et al. Using music on the prevention of delirium in patients after coronary artery bypass graft surgery: a randomized clinical trial. J Cardiothorac Vascular Anesth. Published online September 9, 2022. doi:10.1053/j.jvca.2022.09.007