rTMS May Improve PTSD in Eating Disorders

HealthDay News — Repetitive transcranial magnetic stimulation (rTMS) of the dorsomedial prefrontal cortex (DMPFC) seems to be beneficial for treatment of posttraumatic stress disorder (PTSD) in patients with eating disorders, according to research published online in the International Journal of Eating Disorders.

D. Blake Woodside, MD, from the University Health Network in Toronto, and colleagues presented a case series of 14 subjects with eating disorders and comorbid PTSD who received 20-30 neuronavigated DMPFC-rTMS treatments.

The researchers observed a reduction in the PTSD checklist-Civilian scores of 51.99% ± 27.24% overall (from a mean of 54.29 ± 19.34 to 24.86 ± 17.43 for before and after treatment). Eight of the 14 patients showed an improvement of more than 50%. 

There was an improvement in the Difficulties in Emotional Regulation Scale scores of 36.02% ± 24.24% overall (from 140.00 ± 22.09 to 89.29 ± 38.31 for before and after treatment). Five of the 14 subjects achieved improvement of more than 50%.

“These data may suggest that DMPFC-rTMS could be helpful in the treatment of PTSD in some eating disorder patients,” the authors write.

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Woodside DB, Colton P, Lam E, Dunlop K, Rzeszutek J, Downer J. Dorsomedial prefrontal cortex repetitive transcranial magnetic stimulation treatment of posttraumatic stress disorder in eating disorders: An open-label case series [published online August 16, 2017]. Int J Eat Disord. doi:10.1002/eat.22764