Treatment of ICDs

The main treatment for ICDs is stopping drug therapy or dose reduction, Dr. Weintraub suggested. “Deep brain stimulation (DBS) — which can lead to dose reduction — psychopharmacology (antidepressants, naltrexone), and psychotherapy (cognitive behavioral therapy), may all be beneficial,” he said.

The majority of patients with PD who take DAs or levodopa do not go on to develop ICDs, and the dopaminergic effects may not appear immediately in patients who do, so monitoring is an important part of PD therapeutic management. The potential for ICDs is generally not discussed early in the course of PD, Dr Weintraub explained, but usually comes up later, after treatment is initiated. “A patient really should be notified of the possibility of developing an ICD before initiating any dopaminergic treatment for PD, particularly dopamine agonists,” he said. “And then it should be asked about at all clinical visits, as ICDs can have their onset years after initiating treatment.”

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This article originally appeared on Neurology Advisor