Ketamine was originally approved by the FDA as an anesthetic, but is increasingly being used to treat mood disorders such as treatment-resistant depression, anxiety disorders, and PTSD.
For persons with a previous diagnosis of generalized anxiety disorder (GAD), factors associated with being in complete mental health (CMH) include female gender, older age, being married, and reporting good to excellent physical health.
In an analysis of polygenic risk scores, the researchers identified significant overlap between anxiety and major depressive disorder, as well as PTSD.
For both patients with ulcerative colitis and those with Crohn disease, psychiatric diagnoses were more common in those who were elderly (greater than 65 years old), women, and white, and those with psychiatric conditions more frequently had a history of alcohol abuse, tobacco and substance abuse, personality disorder, and corticosteroid use.
The authors highlighted limitations, including the low quality of studies available based on the high risk of bias in RCTs and heterogeneity of the study designs.
Data from a multisite study of the effectiveness of cognitive behavioral therapy (CBT) support process-focused CBT as a means of reducing social anxiety.
