Responses to treatment depend on the target chosen, with 5 targets yielding positive outcomes, including the ventral anterior limb of the internal capsule, subthalamic nucleus, nucleus accumbens, ventral capsule/ventral striatum, or inferior thalamic peduncle, all involving fronto-striato-thalamocortical circuits.
Results showed a mean change from baseline of -9.28 points (95% CI, -10.23 to -8.32) on the HAM-A total score in patients treated with troriluzole compared with -9.35 points (95% CI, -10.34 to -8.36) with placebo (P =.917).
Depression, anxiety, and reduced quality of life are seen more frequently in patients with atopic eczema—and these associations imply that it may be more than just a skin disease.
The study highlights the significant burden of social anxiety disorder among youth, particularly those with a parental history of psychiatric symptoms.
Katlein França, MD, PhD, spoke with Dermatology Advisor about the use of the behavior therapy technique “habit reversal training” (HRT) for the treatment of trichotillomania, excoriation disorder, and itch.
For persons with a previous diagnosis of generalized anxiety disorder (GAD), factors associated with being in complete mental health (CMH) include female gender, older age, being married, and reporting good to excellent physical health.
In an analysis of polygenic risk scores, the researchers identified significant overlap between anxiety and major depressive disorder, as well as PTSD.
