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Anxiety Associated With Blunted Ventromedial Prefrontal Cortex Response

In a crossover randomized clinical trial, women with generalized anxiety disorder and age-matched control participants underwent fMRI during randomized intravenous bolus infusions of isoproterenol and saline in an effort to ascertain if abnormal physiological, perceptual, or neural responses during peripheral β-adrenergic stimulation indicate interoceptive dysfunction.
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