A large twin study shows that genetics have a major influence on whether attention deficit/hyperactivity disorder (ADHD) symptoms decrease or persist as children grow older.

Furthermore, these genetic influences are mostly separate from those that determine severity of symptoms at baseline, report Jean-Baptiste Pingault (University College London, UK) and study co-authors.

Findings differed for hyperactivity/impulsivity and for inattention symptoms, with the former being governed mostly by additive genetic effects and decreasing markedly over time, whereas the latter were more influenced by dominant genetic effects and remained fairly stable over time.

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