A global status report published in Addiction indicates that the mortality rate associated with substance use was highest in low and middle income countries, and that worldwide attributable disability-adjusted life years (DALYs) were highest for tobacco and alcohol use.

Global data on drug use, substance dependence, and substance-attributable mortality and disease burden were captured from reports from the World Health Organization, the United Nations Office on Crime and Drugs, and the Institute for Health Metrics and Evaluation. In 2015, the estimated prevalence in the adult population was 18.3% for heavy episodic alcohol use; 15.2% for daily tobacco smoking; and 3.8%, 0.77%, 0.37%, and 0.35% for past-year cannabis, amphetamine, opioid, and cocaine use, respectively. European regions had the highest prevalence of heavy alcohol and daily tobacco use, while high-income North America had the highest prevalence of cannabis, opioid, and cocaine dependence.

Globally, the age-standardized prevalence was 843.2, 259.3, 220.4, 86.0, and 52.5 per 100,000 people for alcohol, cannabis, opioids, amphetamines, and cocaine dependence, respectively. Attributable disability-adjusted life-years (DALYs) were 170.9 million for tobacco, 85.0 million for alcohol, and 27.8 million for illicit drugs. Substance-attributable mortality rates were 110.7, 33.0, and 6.9 deaths per 100,000 people for tobacco, alcohol, and illicit drugs, respectively. Eastern Europe had the highest attributable mortality rates and DALYs for alcohol and illicit drug use, while Oceania had the highest attributable mortality rates and DALYs for tobacco.

Continue Reading

Related Articles

Alcohol and tobacco use alone were attributable to nearly 256 million DALYs, with illicit drugs further contributing to the disease burden associated with substance use. Geography was a predictive factor for certain patterns of substance abuse and subsequent risks. As such, researchers proposed that future projects investigate the “geographical and temporal trends in substance use and its disease burden” in order to fully elucidate and address global substance abuse trends.


Peacock A, Leung J, Larney S, et al. Global statistics on alcohol, tobacco and illicit drug use: 2017 status report [published online May 10, 2018]. Addiction. doi:10.1111/add.14234