For US veterans with unhealthy alcohol use, reducing drinking may improve or resolve various conditions including pain interference symptoms and substance use, although most correlations are not significant.
The most notable increase in e-cigarette use from 2014 to 2018 occurred among younger-adult never smokers and near-term quitters (those who quit combustible cigarettes one to eight years before).
Nicotine electronic cigarettes improve long-term smoking cessation compared with nicotine replacement therapy.
For US adults with problem substance use who use nonmedical opioids, the odds of opioid use are increased on days when cannabis is used.
This study provides an empirical examination of coping motive pathways to alcohol problems during the early stages of the COVID-19 pandemic.
Opioid products approved by the FDA between 1997 and 2018 relied on short- or intermediate-term studies that did not adequately analyze safety outcomes.
Investigators revealed distinct neuronal and non-neuronal epigenetic signatures and identified a locus in the proximity of the gene encoding tyrosine kinase FYN as the most affected region in neurons.
Adults with chronic back pain who had adverse allergic reactions to NSAIDs are at higher risk for developing an opioid use disorder.
There have been few studies that have examined the specificity of mood disorder subtypes among the children of parents with both major subtypes of mood disorders and controls based on prospective tracking across the transition from childhood to adulthood.
Alcohol use disorder hospitalizations increased from 1998 to 2016, while in-hospital mortality for patients hospitalized with Alcohol use disorder decreased.