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Reducing Drinking May Improve Pain Interference Symptoms

For US veterans with unhealthy alcohol use, reducing drinking may improve or resolve various conditions including pain interference symptoms and substance use, although most correlations are not significant.

Young Adult Never Smokers Show Growth in E-Cigarette Use

The most notable increase in e-cigarette use from 2014 to 2018 occurred among younger-adult never smokers and near-term quitters (those who quit combustible cigarettes one to eight years before).

Electronic Cigarettes Improve Long-Term Smoking Cessation

Nicotine electronic cigarettes improve long-term smoking cessation compared with nicotine replacement therapy.

For Substance Abusers, Odds of Opioid Use Increase With Cannabis Use

For US adults with problem substance use who use nonmedical opioids, the odds of opioid use are increased on days when cannabis is used.

Factors Impacting Coping-Related Alcohol Use During COVID-19 Pandemic

This study provides an empirical examination of coping motive pathways to alcohol problems during the early stages of the COVID-19 pandemic.

Previously FDA-Approved Opioid Products Did Not Have Adequate Safety Assessment

Opioid products approved by the FDA between 1997 and 2018 relied on short- or intermediate-term studies that did not adequately analyze safety outcomes.

FYN Gene Linked to Heroin Use Disorder Treatment

Investigators revealed distinct neuronal and non-neuronal epigenetic signatures and identified a locus in the proximity of the gene encoding tyrosine kinase FYN as the most affected region in neurons.

Reported NSAID Allergy Increases Risk for OUD in Chronic Back Pain

Adults with chronic back pain who had adverse allergic reactions to NSAIDs are at higher risk for developing an opioid use disorder.

Associations Found Between Parents, Children, and Certain Mood Disorders

There have been few studies that have examined the specificity of mood disorder subtypes among the children of parents with both major subtypes of mood disorders and controls based on prospective tracking across the transition from childhood to adulthood.

1998 to 2016 Saw Rise in Alcohol Use Disorder Hospitalizations

Alcohol use disorder hospitalizations increased from 1998 to 2016, while in-hospital mortality for patients hospitalized with Alcohol use disorder decreased.