The US Food and Drug Administration has provided fast-track approval for the nonclinician use of Evzio, an easy-to-use autoinjectable device with a single dose of naloxone for the reversal of opioid overdose.
Prescription opioid misuse is more common among binge drinkers, with the prevalence of opioid misuse increasing with binge drinking frequency.
Early-life exposure to fine particulate matter (PM2.5) is associated with a reduction in fundamental cognitive abilities.
Current guidelines include recommendations on how to prescribe methylphenidate, but lack of recommendations regarding the long-term use of the drug.
There is variability in data relating to the safety of lithium during breastfeeding.
Although some pharmacological agents may help improve abstinence and treatment retention in patients with cocaine use disorder, the majority of these drugs are ineffective for treating this condition.
Adhansia XR (methylphenidate HCl extended-release capsules) is expected to be available as of July 15, 2019 for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years of age and older, according to Adlon Therapeutics.
Anxiety and stress-related phenotypes correlated with such traits as depression and obesity and smoking.
Children of parents with opioid use had a 2-fold increased risk for suicide attempts vs children of matched controls.
The growth of drug spending in the United States associated with government-protected market exclusivity is likely to continue.
Adult patients with treatment-resistant depression showed a favorable improvement in symptoms after a course of esketamine twice-weekly for 28 days.
Only one-third of Philadelphia pharmacies carry naloxone nasal spray and many pharmacies require a physician’s prescription.
Employees with heavier workloads or who are burned out are more likely to emotionally eat and exercise less.
The Drug Enforcement Administration (DEA) has placed Zulresso (brexanolone; Sage Therapeutics), a treatment for postpartum depression, into Schedule IV of the Controlled Substances Act.
In the first month after the release of the Netflix drama 13 Reasons Why in spring 2017, there was a 15% increase in suicides in the target audience, 10- to 19-year-olds.
Stimulus control therapy and sleep restriction therapy are viable single-component treatments for chronic insomnia.
In addition to differing tryptophan plasma levels during pregnancy and postpartum periods, women with postpartum depressive symptoms have higher plasma levels of kynurenine and kynurenic acid.
An increase in the suicide rate among female youth has contributed to a reduction in the historically large gap in suicide rates between sexes.
The Opioid Safety Initiative has been effective for decreasing opioid prescriptions among patients undergoing total knee arthroplasty.
More frequent manic/mixed and depressive episodes were associated with an increased risk for Parkinson disease.
Weak physical performance on tests of the upper and lower body is associated with depressive and anxiety symptoms in midlife women.
For patients who do not respond to pharmacologic and psychological interventions, high-frequency dTMS may reduce symptomology.
Researchers sought to determine risk factors for hospitalization in children with atopic dermatitis.
Physician misconduct is being underreported and most Americans do not know where to file a complaint.
The prevalence of non-suicidal self-injury ranged from 38.04 to 52.97 percent for sexual-minority youth between 2005 and 2017.
A history of such childhood trauma as emotional neglect and abuse, in addition to genetic variants, are linked to suicidal behavior in individuals with bipolar disorder.
Moderate to severe depressive symptoms after a stay in an intensive care unit are associated with decreased income, lower education, and higher functional dependence.
When screening for depression in adolescents with type 1 diabetes, the PHQ-9 had a higher sensitivity compared with the PROMIS questionnaire.
The treatment utilizes a proprietary drug delivery platform which consists of 2 functional film coatings: the first layer delays the initial drug release for up to 10 hours and the second layer helps control the release rate of the active ingredient throughout the day.
Perinatal maternal depressive symptoms were consistently associated with brain development in offspring at age 10 years.
Exercise and cognitive behavioral therapy can improve depression outcomes in adults with type 2 diabetes.
For callers reporting heroin use, many buprenorphine prescribers do not offer new appointments or rapid access to buprenorphine.
There were no medical malpractice claims against direct-to-consumer telemedicine professionals or services among the reported cases identified in this study.
For adolescents and young adults, the rate of opioid prescribing in emergency departments is high.
Somatic items on the PHQ-9 questionnaire show less discriminatory value than the non-somatic items when identifying major depressive disorder.
For youth with or at risk for overweight, weight-based teasing (WBT) is associated with a greater gain in body mass index (BMI) and fat mass.
High costs are associated with physician turnover and reduced clinical hours attributed to burnout.
A cognitive behavioral therapy-based intervention was associated with reductions in conduct problems, suicidality, and emotional symptoms in high-risk adolescents.
Integrated stepped alcohol treatment (ISAT) reduces alcohol consumption in patients with HIV and a known drinking problem.
Buprenorphine treatment may be more available to individuals who are white, use self-pay, or have private insurance.
Current research signifies the validity and fairness of the Kutcher Adolescent Depression Scale for assessing depression among adolescents, regardless of their marital status or sex.
Messenger RNA and MicroRNA can be used as viable predictors of suicidal behavior.
Findings of the study revealed that the frequency of adverse events compared with placebo was statistically similar in patients receiving SSRIs but was higher in patients taking SNRIs.
Patients at high risk of opioid overdose rarely receive prescriptions for naloxone, despite many interactions with the health care system.
Regulation of the intestinal microbiota appears to be effective for improving anxiety symptoms, with nonprobiotic interventions performing better than probiotic interventions.
Researchers suggest a care ethics approach to address specific needs of patients who struggle with thoughts of being a burden to others.
The ACP has issued a position paper that examines the professional duties and principles that should guide the response of colleagues and the profession to physician impairment.
OCD symptoms alleviation during the postpartum period was associated with hyperthymic temperament and a history of decreased OCD symptoms following a previous birth.
Both conditions will be included in the 11th edition of the WHO International Classification of Diseases.
The US Food and Drug Administration is seeking feedback from healthcare professionals on its proposal to offer fixed-quantity blister packaging for a select number of opioid medications.
