This Viewpoint describes the legalization of marijuana in Colorado and the unexpected and adverse health effects reflected in hospital data collected so far.

The legalization of marijuana in Colorado has had complex effects on the health of its citizens. Physicians have the responsibility to present a balanced perspective, identifying both the potential health benefits and risks associated with marijuana use. In this Viewpoint, we discuss the history of marijuana policy in Colorado and the expected and unexpected effects of increased marijuana availability. Other states considering marijuana policy liberalization may learn from the experiences in Colorado.

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