Depression Often Untreated in Dialysis Patients

HealthDay News — Depression is common among kidney failure patients undergoing dialysis, but efforts to get them on antidepressants often fail, according to research published online Jan. 26 in the Clinical Journal of the American Society of Nephrology.

The study included 101 dialysis patients who completed monthly questionnaires about depression symptoms. They were followed for at least one year. Thirty-nine patients were diagnosed with depression, based on assessments from a total of 147 sessions with health care staff.

The researchers found that 70% of sessions showed evidence that the patient was getting antidepressant treatment. In 70% of cases where a nurse recommended that the patient intensify treatment, the patient refused to do so. In 11 of 18 cases where patients agreed they needed depression medication, renal providers were unwilling to prescribe it. The main reason patients refused to take antidepressants was because they felt their depression was attributable to an acute event, chronic illness, or dialysis.

“Our study demonstrated that many patients on chronic hemodialysis have depressive symptoms but do not wish to receive aggressive treatment to alleviate these symptoms,” study co-leader Steven Weisbord, MD, of the VA Pittsburgh Healthcare System, said in a journal news release. “We also noted that when patients are willing to accept treatment, renal providers commonly do not prescribe treatment.”

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  1. Pena-Polanco JE, Mor MK, Tohme FA, Fine MJ, Palevsky PM, Weisbord SD. Acceptance of Antidepressant Treatment by patients on hemodialysis and their renal providers. CJASN. 2017; doi:10.2215/​CJN.07720716
  2. Hackett ML, Jardine MJ. We need to talk about depression and dialysis: but what questions should we ask, and does anyone know the answers? CJASN. 2017; doi:10.2215/​CJN.13031216