Generic Name and Formulations:
Hepatitis B vaccine (recombinant), adjuvanted (formulated to contain HBsAg 20mcg + CpG 1018 3000mcg) per 0.5mL dose; soln for IM inj; preservative-free.
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Indications for HEPLISAV-B:
Hepatitis B immunization.
Give IM inj in deltoid muscle. ≥18yrs: 2 doses (0.5mL each) 1 month apart.
<18yrs: not established.
Have appropriate medical treatment available to manage possible anaphylactic reactions. Immunocompromised. Pregnancy. Nursing mothers.
Concomitant immunosuppressants: may get sub-optimal response. Concomitant immune globulin; give separately using different syringes at different inj sites. May interfere with lab tests.
Local reactions (eg, pain, redness, swelling), fatigue, headache, malaise; anaphylaxis.
To register pregnant patients, call (844) 443-7734.
Single-dose vials—1, 5
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