Generic Name and Formulations:
Estazolam 1mg, 2mg; scored tabs.
Various generic manufacturers
Indications for Estazolam:
Short-term treatment of insomnia.
Initially 1mg at bedtime. May increase to 2mg nightly. Small or debilitated elderly: initially 0.5mg.
<18yrs: not recommended.
Concomitant ketoconazole, itraconazole. Pregnancy (Cat.X).
Drug or alcohol abuse. Suicidal tendencies. Depression. Renal, hepatic, or respiratory impairment. Avoid abrupt cessation after prolonged use. Elderly. Debilitated. Nursing mothers: not recommended.
Potentiates CNS depression with alcohol, other CNS depressants. Caution with CYP3A inhibitors (eg, nefazodone, fluvoxamine, cimetidine, diltiazem, isoniazid, other macrolides): consider dose reduction.
CNS depression, complex sleep-related behaviors (eg, sleep-driving), hypokinesia, dizziness, incoordination, confusion, constipation, anxiety, paradoxical excitement; anaphylaxis, angioedema.
Formerly known under the brand name Prosom.
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Age of Onset of Bipolar Disorder Linked With Substance Use Disorders
- Rapid Cycling in Bipolar Disorder: Overview and Expert Perspectives
- Low Testosterone Linked With Social Anxiety in Boys With Klinefelter Syndrome
- Posttraumatic Stress Disorder Associated With Reduced Brain Volume
- First-Episode Drug-Naive Patients With Schizophrenia More Likely to Attempt Suicide
- The Psychology of Hoarding Disorder: Approaches for Treatment
- Mind-Body Therapy and Psychiatry: Ancient Tools for Modern Practice
- Smartphone Applications for Depression and Anxiety: Are They Ready for Widespread Use?
- The Many Misconceptions of Catatonia: Treatment Is Often Successful With the Right Knowledge
- Marijuana Use Associated With Poorer Depression Outcomes, Increased Suicidal Ideation