Indications for VELTASSA:
Limitations of Use:
Not for emergency treatment for life-threatening hyperkalemia due to its delayed onset of action.
Give at least 3hrs before or 3hrs after other oral medications. Take without regard to food; mix with water. Initially 8.4g once daily. Adjust dose in 8.4g increments as needed at ≥1-week intervals to obtain desired serum potassium target range; max 25.2g/day.
Binding to other oral medications.
Avoid in severe constipation, bowel obstruction or impaction, abnormal post-op bowel motility disorders. Monitor serum potassium, magnesium. Consider magnesium supplementation if low serum levels develop.
May reduce absorption and efficacy of other oral medications; separate dosing by at least 3hrs.
Constipation, hypomagnesemia, diarrhea, nausea, abdominal discomfort, flatulence.
Generic Drug Availability:
Single-use packets (8.4g)—4, 30; (16.8g, 25.2g)—30