Colorectal disorders:

Indications for LIALDA:

To induce remission in active, mild-to-moderate ulcerative colitis; and to maintain remission of ulcerative colitis.

Adult:

≥18yrs: Swallow whole with a meal. 2.4–4.8g once daily for up to 8 weeks. Maintenance: 2.4g once daily.

Children:

<18yrs: not established.

Warnings/Precautions:

Sulfasalazine allergy. Upper GI tract obstruction (eg, pyloric stenosis) may delay onset of action. Discontinue if acute intolerance syndrome is suspected. Conditions predisposing to myocarditis or pericarditis. Atopic dermatitis or eczema: may have more severe photosensitivity reactions. Renal or hepatic impairment. Monitor renal function prior to and periodically during therapy. Elderly (monitor CBCs). Pregnancy. Nursing mothers: monitor infants.

Pharmacologic Class:

Aminosalicylate.

Interactions:

Increased toxicity with nephrotoxic drugs (eg, NSAIDs). Increased risk for blood disorders, bone marrow failure, and associated complications with azathioprine or 6-mercaptopurine and/or other drugs known to cause myelotoxicity. May cause elevated test results in measuring urinary normetanephrine.

Adverse Reactions:

Ulcerative colitis, headache, flatulence, abnormal LFTs, abdominal pain; acute intolerance syndrome (cramping, bloody diarrhea, fever, headache, rash), renal impairment, cardiac hypersensitivity reactions, pancreatitis (rare).

Generic Availability:

YES

How Supplied:

Tabs—120

Pricing for LIALDA

1.2g tablet (Qty: 120)
Appx. price $381
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