Select therapeutic use:

Allergies:

Indications for Diphenhydramine Injection:

Allergic disorders where oral form is impractical or contraindicated. Adjunct in anaphylaxis. Allergic reactions to blood or plasma.

Adult:

10–50mg IV or deep IM; max 400mg/day.

Children:

Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.

Contraindications:

Neonates. Premature infants. Acute asthma. Concomitant diphenhydramine products (including topicals).

Warnings/Precautions:

Asthma and lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Sodium-restricted diet. Children. Pregnancy (Cat.B in 3rd trimester): not recommended. Nursing mothers.

Pharmacologic Class:

Antihistamine.

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.

Adverse Reactions:

Drowsiness, dizziness, anticholinergic effects, excitability in children.

How Supplied:

Caps—24, 48; Tabs—24, 48, 100; Dye-free softgels—24; Allergy Liq—4oz, 8oz; Dye-free Liq—4oz; Inj—contact supplier

Nausea:

Indications for Diphenhydramine Injection:

Motion sickness.

Adult:

10–50mg IV or deep IM; max 400mg/day.

Children:

Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.

Contraindications:

Neonates. Premature infants. Nursing mothers.

Warnings/Precautions:

Asthma. Lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Children. Pregnancy (Cat.B).

Pharmacologic Class:

Antihistamine.

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.

Adverse Reactions:

Drowsiness, dizziness, anticholinergic effects, gastritis, paradoxical excitement, blood dyscrasias, hypotension.

How Supplied:

Contact supplier.