Depressive Disorder

Careful Assessment for Depression Required for Patients With IBD

Careful Assessment for Depression Required for Patients With IBD

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Single-question self-assessment is not a sufficient marker of identifying depression in people with IBD.

Do Biologic Agents Lower Depression Risk in Psoriasis?

Do Biologic Agents Lower Depression Risk in Psoriasis?

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Treatment with biologic agents in psoriasis may reduce risk for depressive symptoms.

Depression Screening Tools Accurate in Post-Acute Coronary Syndrome

Depression Screening Tools Accurate in Post-Acute Coronary Syndrome

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Cognitive behavioral therapy combined with antidepressant medication modestly improves psychosocial outcomes.

Near-Infrared Phototherapy Brings Remission for Depressed Patients

Near-Infrared Phototherapy Brings Remission for Depressed Patients

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In patients with comorbid depression and TBI, multi-Watt transcranial near-infrared light therapy is effective.

Psychosocial Intervention Improves Early Adherence to Antidepressants

Psychosocial Intervention Improves Early Adherence to Antidepressants

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Early adherence is an especially problematic, significant and modifiable barrier to quality care for depression.

Anxiety, Depression, Suicidal Ideation More Common in Atopic Dermatitis

Anxiety, Depression, Suicidal Ideation More Common in Atopic Dermatitis

Atopic dermatitis is associated with depression, anxiety, and suicidal ideation.

Depression Treatment Preference May Not Affect Outcomes

Depression Treatment Preference May Not Affect Outcomes

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Patients matched to their preferred treatment were more likely to complete the trial but not more likely to achieve depression remission.

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Hundreds of active pilots manage depressive symptoms without the possibility of treatment due to fear of negative career impact.

Relationship Between Depression and Stable Angina Outcomes

Relationship Between Depression and Stable Angina Outcomes

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The strongest predictor of depression in patients with chronic stable angina was an episode of depression within the past 10 years.

Depressive Symptoms Linked to Shorter Survival With Lung Cancer

Depressive Symptoms Linked to Shorter Survival With Lung Cancer

Depression symptoms at baseline correlated with increased mortality among participants with early- but not late-stage disease.

Gene Sets Altered Across Brain Regions in Schizophrenia, Bipolar Disorder & MDD

Gene Sets Altered Across Brain Regions in Schizophrenia, Bipolar Disorder & MDD

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Until now, the majority of postmortem research that has examined functionally related gene sets has been limited to a single disorder or region of the brain.

Sertraline Prevents Depression Following Traumatic Brain Injury

Sertraline Prevents Depression Following Traumatic Brain Injury

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Approximately 80% of depressive episodes have their onset during the first six months following traumatic brain injury.

Pupillometric Analysis For Assessment of Depression Recurrence

Pupillometric Analysis For Assessment of Depression Recurrence

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Pupillary reactivity to emotional stimuli has been investigated to provide objective information about the risk for recurrence of depressive symptoms in women.

Mood Disorders and the Disrupted Gut Microbial Milieu

Mood Disorders and the Disrupted Gut Microbial Milieu

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Lower diversity of microbial populations in the human gut has been identified in individuals with major depressive disorder.

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

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Dr. Roger McIntyre suggests that the clinical relevance of cognitive dysfunction for any individual patient can only be adjudicated on a case-by-case basis.

Whole Body Hyperthermia: The Future of Depression Treatment?

Whole Body Hyperthermia: The Future of Depression Treatment?

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Researchers investigated the lasting effects of whole body hyperthermia (WBH) in the first randomized, double-blind, [placebo]-controlled study of WBH for the treatment of MDD.

Does Impaired Cognition Precede Depression?

Does Impaired Cognition Precede Depression?

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Dysfunction across several cognitive domains is often concomitant with depression.

"Frequent Flyers" in Emergency Department More Likely to Have Depression

"Frequent Flyers" in Emergency Department More Likely to Have Depression

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"Detecting depression in the emergency department is of utmost importance," Dr. Brickman and colleagues wrote in their publication.

EEG Registry Reduces Trial-and-Error Approach to Depression Treatment

EEG Registry Reduces Trial-and-Error Approach to Depression Treatment

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The registry contains more than 10,000 EEGs and 38,000 pharmacological outcomes, and is accessible to clinicians worldwide.

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

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mBDNF/proBDNF ratio could potentially serve as a novel biomarker for mood disorders.

Association Between Polymorphisms in the FKBP5 Gene and MDD

Association Between Polymorphisms in the FKBP5 Gene and MDD

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It is hypothesized that multiple single nucleotide polymorphisms (SNPs) work together to influence risk of complex neuropsychiatric disorders such as depression.

Evidence for a Role of Neuropeptide Y Receptor Variant in Depression

Evidence for a Role of Neuropeptide Y Receptor Variant in Depression

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Genetic variation can increase the predisposition to major depressive disorder.

The Neuroanatomy of, and Cognitive Deficits in, Depression: A Brief Overview

The Neuroanatomy of, and Cognitive Deficits in, Depression: A Brief Overview

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Atrophy of numerous structures within the central nervous system has been observed in persons suffering from depression.

Late-onset Depression Associated with Elevated Dementia Risk

Late-onset Depression Associated with Elevated Dementia Risk

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Dementia risk was particularly elevated in patients with depression who had higher scores on cognitive tests at baseline.

Investigating Risk Factors for Postpartum Depression

Investigating Risk Factors for Postpartum Depression

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The First Baby Study at Penn State College of Medicine includes more than 3 000 women in Pennsylvania having their first baby.

Cognitive Function in Depression: The Role of Melancholic Features

Cognitive Function in Depression: The Role of Melancholic Features

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Individuals diagnosed with melancholic major depressive disorder presented with more severe symptoms of depression compared with persons with non-melancholic depression.

ACC Activation to Reward Predicts Response to Psychotherapy for MDD

ACC Activation to Reward Predicts Response to Psychotherapy for MDD

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Sustained anterior cingulate cortex activation during rewarding events predicted better treatment response to Behavioral Activation Treatment for Depression.

Meta-Analysis: Depression Common in Patients Discharged From ICU

Meta-Analysis: Depression Common in Patients Discharged From ICU

Risk highest among patients with psych symptoms pre-ICU/psych distress symptoms while in ICU

Psychosocial and Demographic Predictors of Depression Among Individuals With Bipolar Disorder and Schizophrenia

Psychosocial and Demographic Predictors of Depression Among Individuals With Bipolar Disorder and Schizophrenia

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Bipolar disorder and schizophrenia are characterized by significant genetic overlap, as well as significant clinical presentation overlap.

Intergenerational Transmission of Risk for Depression

Intergenerational Transmission of Risk for Depression

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Grandchildren with both a depressed parent and depressed grandparent were at highest risk for MDD.

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