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Efficacy, Safety of Long-Term Ketamine Administration Still In Question

Ketamine, originally approved by the FDA in 1970 as an anesthetic, is increasingly being recognized as an option in treatment-resistant depression.

Probiotics, Depression, and the Role of Inflammation

Researchers examined evidence suggesting that probiotics may exert antidepressant effects via anti-inflammatory mechanisms.

Predicting Poststroke Depression: Biomarkers and Beyond

As depression is one of the most common psychiatric disorders following acute stroke and can be predictive of poor outcomes, identifying biomarkers to recognize the ...

The Opioid System: The Foundation for Social Risk and Reward

The opioid system is responsible for social pain and reward in the brain; therefore, understanding its underpinnings may help clinicians manage patients with depression and ...

Transcranial Direct Current Stimulation Promising for Major Depressive Disorder

With better understanding of the underlying mechanisms of transcranial direct current stimulation, clinicians will be better equipped to identify the optimal management of their patients ...

Depression in Youth: Underdiagnosed and Deadly

The mechanics of therapy look quite different for younger patients, whose experiences with depression vary by age, emotional vocabulary, cognitive development, and experiences with trauma.

Light Therapy Effective for Older Adults with Nonseasonal Depression

Rapid onset of antidepressant effects, mild and infrequent adverse effects, and cost-effectiveness position light therapy as an alternative to pharmacologic treatments for depression.

News Articles

No Significant Differences in Epidermal Growth Factor, Fibroblast Growth Factor-2 in Elderly With MDD

No Significant Differences in Epidermal Growth Factor, Fibroblast Growth Factor-2 in Elderly With MDD

Findings indicated that no significance of epidermal growth factor levels and fibroblast growth factor-2 levels were found in elderly patients with major depressive disorder.

Self-Report Cognitive Questionnaires Predict Work Improvement in Depression

Self-Report Cognitive Questionnaires Predict Work Improvement in Depression

Researchers studied the relationship between self-reported cognitive complaints and work functioning in employed patients with major depressive disorder treated with desvenlafaxine.

Major Depression Linked to Self-Esteem, Depression Severity, Hopelessness

Major Depression Linked to Self-Esteem, Depression Severity, Hopelessness

Investigators created a prognostic index to identify factors to predict long-term depression severity after successful and quality acute treatment for major depressive disorder.

Trauma, Stress, and More Linked to Depressive Disorders in College Freshmen

Trauma, Stress, and More Linked to Depressive Disorders in College Freshmen

As major depressive disorder is common among college students, researchers sought to determine factors that contribute to this condition, particularly among college freshmen.

Clinical Depression Associated With Hearing Loss in Older Hispanic Populations

Clinical Depression Associated With Hearing Loss in Older Hispanic Populations

Hearing loss appears to be independently associated with clinically significant depressive symptoms in older Hispanic individuals.

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