Dementia

Dementia Often Misclassified With Brief Cognitive Assessments

Dementia Often Misclassified With Brief Cognitive Assessments

When using brief cognitive assessments, dementia is often misclassified.

Fruits, Veggies, Orange Juice May Protect Men's Memory

Fruits, Veggies, Orange Juice May Protect Men's Memory

Higher consumption of vegetables and fruits is associated with lower odds of future memory loss in men.

Positive Link Between Air Pollution, Diagnosis of Dementia

Positive Link Between Air Pollution, Diagnosis of Dementia

There is a positive association between residential levels of air pollution and being diagnosed with dementia.

Prevalence of Alzheimer Disease, Related Dementia Set to Double

Prevalence of Alzheimer Disease, Related Dementia Set to Double

The burden of Alzheimer disease and related dementias (ADRD) is expected to increase to 3.3% in the United States by 2060.

PET imaging of tau may help distinguish Alzheimer Disease from other neurodegenerative disorders

In this cross-sectional study, the tau marker [18F]flortaucipir accurately distinguished Alzheimer Disease dementia from other non-AD neurodegenerative disorders about 90% of the time.

Improved cardiovascular health associated with lower incidence of dementia in older adults

In this prospective cohort study, older patients with more optimal cardiovascular health metrics had a lower rate of developing dementia in a dose-dependent manner.

Reducing Off-Label Quetiapine Prescribing the Old-Fashioned Way: Snail Mail

Reducing Off-Label Quetiapine Prescribing the Old-Fashioned Way: Snail Mail

By

Despite the associated risk for death and cognitive decline, "off-label" prescribing of antipsychotics in patients with dementia has increased.

Cortisol Levels May Contribute to Global Cognitive Decline in Elderly Adults With Depression

Cortisol Levels May Contribute to Global Cognitive Decline in Elderly Adults With Depression

By

These data indicate that cortisol levels may contribute to the cognitive decline observed in elderly adults with late-life depression.

VAT Score Improves Predictive Value of Mini-Mental State Examination for Dementia

VAT Score Improves Predictive Value of Mini-Mental State Examination for Dementia

Administering the Visual Association Test improves the predictive value of the Mini-Mental State Examination score for dementia.

Significant Rates of Major Depressive Disorder Found in Dementia

Significant Rates of Major Depressive Disorder Found in Dementia

By

Patients with dementia had an increased prevalence of major depressive disorder.

Apathy Associated With Increased Risk for Dementia

Apathy Associated With Increased Risk for Dementia

By

These findings have high clinical relevance because patients with apathy are likely to withdraw from care.

Intensive Blood Pressure Control Cuts Combined Mild Cognitive Impairment, Dementia Risk

Intensive Blood Pressure Control Cuts Combined Mild Cognitive Impairment, Dementia Risk

By

In the previous SPRINT study, researchers compared an intensive BP reduction strategy (target systolic BP <120 mmHg) vs standard BP reduction strategy (target systolic BP <140 mmHg).

Visual Hallucinations in Dementia and Parkinson Disease: Assessment of Patient Experiences

Visual Hallucinations in Dementia and Parkinson Disease: Assessment of Patient Experiences

By

Patients who felt the situation was "abnormal" were less likely to seek help. This trend was more common in patients with Parkinson disease than patients with dementia, although both described feeling "embarrassed or ashamed."

Telemedicine Intervention for Neuropsychiatric Symptoms in Long-term Care Facilities

Telemedicine Intervention for Neuropsychiatric Symptoms in Long-term Care Facilities

By

Researchers of the DETECT study aim to assess the potential for future implementation of telemedicine consultation for managing neuropsychiatric symptoms in long-term care facilities.

Visual Association Test, MMSE Highly Predictive of Dementia in Older Adults

Visual Association Test, MMSE Highly Predictive of Dementia in Older Adults

By

Using the Visual Association Test along with the Mini Mental State Examination may improve predictive value to screen for cognitive deficits.

Benzodiazepines, Related Drugs Associated With Modestly Increased Risk for Alzheimer Disease

Benzodiazepines, Related Drugs Associated With Modestly Increased Risk for Alzheimer Disease

By

Given the frequent use of benzodiazepines among older people, even a small increase in absolute risk may be a serious matter on a population level.

Higher Blood Pressure at Midlife Increases Risk for Dementia

Higher Blood Pressure at Midlife Increases Risk for Dementia

The risk of dementia is increased in 50-year-olds with blood pressure ≥130 mm Hg, which is below the current threshold for hypertension.

Trials for Investigational Alzheimer Treatment Lanabecestat Discontinued

Trials for Investigational Alzheimer Treatment Lanabecestat Discontinued

By

Phase 3 clinical trials for lanabecestat (Eli Lilly and AstraZeneca), an investigational Alzheimer disease treatment, are being discontinued for futility.

Lifetime Risks Temper Biomarker Tests for Alzheimer Disease Dementia

Lifetime Risks Temper Biomarker Tests for Alzheimer Disease Dementia

The lifetime risks of Alzheimer disease dementia vary considerably by age, gender, and the preclinical or clinical disease state.

Intellectual Activities in Later Life May Cut Dementia Risk

Intellectual Activities in Later Life May Cut Dementia Risk

There is a reduced risk for dementia for older Chinese adults actively participating in intellectual activities.

Greater Wealth Associated With Lower Risk for Dementia in English Study

Greater Wealth Associated With Lower Risk for Dementia in English Study

By

Public health strategies for preventing dementia should target socioeconomic gaps to reduce health disparities and protect the disadvantaged.

Anxiety: Feature of Late-Onset Dementia or Modifiable Risk Factor?

Anxiety: Feature of Late-Onset Dementia or Modifiable Risk Factor?

By

The researchers encouraged clinicians not to rely solely on medication to treat midlife anxiety, as benzodiazepines have been shown to increase mortality in certain groups; they pointed to talk therapy, meditation, and mindfulness-based interventions as possible considerations.

FNIH Launches Project to Identify Biosignatures of Neurodegenerative, Psychiatric Conditions

FNIH Launches Project to Identify Biosignatures of Neurodegenerative, Psychiatric Conditions

By

Multimarker inflammatory biosignatures are expected to facilitate diagnosis and predict treatment outcomes for various central nervous system disorders, particularly Alzheimer disease and major depressive disorder.

Depression in Patients With Dementia May Increase Risk for Heart Disease

Depression in Patients With Dementia May Increase Risk for Heart Disease

By

Clinicians should take depression into careful consideration when treating patients with Alzheimer dementia, as the two conditions combined may predispose patients to cardiovascular disease more than either condition alone.

Clinically Significant Anxiety Tied to Subsequent Dementia Risk

Clinically Significant Anxiety Tied to Subsequent Dementia Risk

These findings indicate that anxiety may be a risk factor for late-life dementia, excluding anxiety that is related to prodromal cognitive decline.

Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics

Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics

By

These results suggest that antipsychotic exposure has no impact on relative mortality.

Anticholinergic Drug Use and Dementia: What's the Link?

Anticholinergic Drug Use and Dementia: What's the Link?

By

The use of certain anticholinergic drugs may increase the risk of future dementia.

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Using hearing aids may slow cognitive decline in later life.

Traumatic Brain Injury Associated With Increased Risk for Dementia

Traumatic Brain Injury Associated With Increased Risk for Dementia

By

These data support the importance of TBI preventative measures and proper management strategies for subsequent dementia.

Association Between Psychosis and Development of Dementia in Older Men

Association Between Psychosis and Development of Dementia in Older Men

By

The findings also suggested that more a more recent diagnosis of psychosis was a greater predictor of the development of dementia, as opposed to cases where patients had been living with psychotic disorder diagnoses for 10 years or more.

Sign Up for Free e-newsletters