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BONJESTA
Nausea
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Drug Name:

BONJESTA Rx

Generic Name and Formulations:
Doxylamine succinate 20mg, pyridoxine HCl 20mg; ext-rel tabs.

Company:
Duchesnay USA, Inc.

Therapeutic Use:

RECENT UPDATES

Monograph added.

Indications for BONJESTA:

Treatment of nausea and vomiting of pregnancy (NVP) in women who do not respond to conservative management.

Limitations Of use:

Not studied in women with hyperemesis gravidarum.

Adult:

Swallow whole. Take on empty stomach with water. ≥18yrs: Day 1: initially 1 tab at bedtime; continue same dose next day if symptoms adequately controlled. If symptoms persist on Day 2, increase to 1 tab in AM and 1 tab at bedtime daily. Max 2 tabs daily.

Children:

<18yrs: not established.

Contraindications:

Concomitant MAOIs; may prolong and intensify anticholinergic effects.

Warnings/Precautions:

Asthma. Increased intraocular pressure. Narrow angle glaucoma. Stenosing peptic ulcer. Pyloroduodenal obstruction. Urinary bladder-neck obstruction. Reevaluate as pregnancy progresses. Nursing mothers: not recommended.

Interactions:

See Contraindications. Concomitant alcohol, other CNS depressants (eg, hypnotic sedatives, tranquilizers): not recommended. Concomitant food may delay onset of action and reduce absorption.

Pharmacological Class:

Antihistamine + Vit. B6 analog.

Adverse Reactions:

Somnolence.

Generic Availability:

NO

How Supplied:

Tabs—60, 100

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