Drug comparisons for mood disorders such as bipolar disorder, major depressive disorder, treatment resistant depression, premenstrual dysphoric disorder, and others.
In pediatric patients with bipolar I depression, long-term treatment with lurasidone 20 mg/day is effective in reducing depressive symptoms.
Investigators compared set-shifting, decision making, and central coherence in patients with bipolar disorder, OCD, and comorbid bipolar disorder with OCD.
These findings indicate a significant modulative effect of social cognition on neurocognition and community functioning in bipolar disorder and thus may be relevant in titrating treatment in patients with varying social cognition levels.
Communities that favor consanguineous marriage should receive sensitive advice on the risks involved to aid in reproductive decision making.
These results highlight the potential utility of incorporating personality functioning assessments into bipolar disorder I treatment plans to fully restore global functioning during remission.
Researchers noted that therapeutic interventions focused on GDF-15 levels may decrease mortality risk and increase longevity in patients with bipolar disorder.
Patients associated with caregivers who received family-focused treatment also demonstrated a significant decrease in depressive symptoms compared with patients associated with caregivers in the control group.
Individuals of African ancestry are more likely misdiagnosed with a disease other than bipolar disorder.
Researchers characterized the psychopathological features in patients with type II bipolar disorder who experienced treatment-emergent mania after exposure to antidepressants.
Patients with type I bipolar disorder had significantly higher fasting triglyceride levels (121.7 mg/dL vs 87.0 mg/dL, P <.01).
Individuals with depressive residual symptoms between episodes may have more of a negative course of illness.
These findings challenge existing concerns about the association of light therapy with manic switching and may be useful for clinicians in developing treatment strategies for patients with bipolar disorder.
Bipolar disorder (31.9%), depression (19.8%), schizophrenia (14.2%), and anxiety disorders (9.1%) were the most common mental health issues reported. Approximately 13% of evacuees with a mental health concern reported a history of post-traumatic stress disorder.
Successful management of both the manic and depressive states in bipolar disorder has been difficult to achieve, despite a broad range of pharmacologic treatments available.
Michael Thase, MD, comments on the potential for lithium in drinking water as a psychiatric prophylactic agent.
Investigators seek the association between psychosis and complication risk after total joint arthroplasty.
Exploring Safe and Effective Treatments for Bipolar Depression: Transcranial Direct Current StimulationJanuary 22, 2018
Transcranial direct current stimulation may be an effective add-on treatment for bipolar depression.
The frequent comorbidity of bipolar disorder and alcohol use disorder presents a significant challenge for clinicians managing patients with these conditions.
Safety and efficacy of lurasidone monotherapy were assessed in children and adolescents with bipolar I depression.
The Oregon Foundation for Reproductive Health recommends that all medical providers ask all female patients of reproductive age if they plan to become pregnant in the next year.
Patients with bipolar I disorder without relapse after 1 year of first treatment had improved neurocognitive functioning.
Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.
Bipolar disorder and borderline personality disorder reflect alternate expressions of the same underlying disorder.
The benefits of psychoeducation for patients with bipolar disorder were mediated by perceived change in illness.
Venlafaxine was superior to lithium in reducing symptoms of both bipolar II depression and anxiety.
A schizophrenia-related polygenic-risk score association gradient was identified across bipolar disorder phenotypes.
The severity of psychotic symptoms in patients with bipolar affective disorder correlated inversely with the response to lithium therapy.
Patients with schizophrenia-spectrum disorders had higher odds of being aggressive than people with bipolar disorder with a recent manic episode.
The ability to track ingestion of medications prescribed for mental illness may be useful for some patients.
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