Pharmacology and Toxicology: Selective Discussion of major nephrotoxins
Does this patient have drug-induced nephrotoxicity? The initial diagnosis of drug-induced nephrotoxicity typically involves detection of abrupt changes in kidney function manifesting as acute increases in serum creatinine, blood urea nitrogen (BUN), or decreased urine output, which is temporally related to initiation or ongoing use of a potentially nephrotoxic drug. The mechanism and presentation of…