Tatyana Hamilton, Author at Psychiatry Advisor

Tatyana Hamilton

All articles by Tatyana Hamilton

Elastosis perforans serpiginosa(Elastosis Perforans Serpiginosum, Lutz-Meischer Disease)

Are You Confident of the Diagnosis? Elastosis perforans serpiginosa (EPS) represents a distinct entity within the spectrum of perforating dermatoses. It is a rare disorder characterized by transepidermal elimination of altered elastic fibers. About one-quarter of cases are associated with an underlying disorder, typically of connective tissue, or with D-penicillamine use. These include Marfan syndrome,…

Acquired Perforating Dermatosis (Perforating Dermatoses [All variants], Elastosis Perforans Serpiginosa, Reactive Perforating Collagenosis, Kyrle’s Disease, Perforating Folliculitis, Perforating Periumbilical Calcific Elastosis, Perforating Disorder of Renal Disease)

Are You Confident of the Diagnosis? In order to be confident in the diagnosis of a perforating disorder, one must acknowledge the historical ambiguity in classifying these disorders. In the past, these disorders have included elastosis perforans serpiginosum (EPS), reactive perforating collagenosis (RPC, pediatric and adult forms), perforating folliculitis (PF), Kyrle’s disease, perforating disorder of…

Kyrle's Disease (hyperkeratosis follicularis et parafollicularis in cutem penetrans)

Are You Confident of the Diagnosis? What you should be alert for in the history A history of diabetes, renal or hepatic disease, and congestive heart failure have been reported as associations with Kyrle’s disease. Up to 10% of renal dialysis patients develop Kyrle’s disease. However, other authors deny any such systemic associations. Curiously, Kyrle’s…

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