Early Stresses Contribute to Schizophrenia
Researchers found data to support their hypothesis that developmental stress vulnerability is the link between a predisposition and environmental triggers in the pathophysiology of schizophrenia.
All articles by Suzanne Bujara
Targeting Inflammation Through Cytokines to Treat Depressive Symptoms
Researchers found a small number of clinical trials that indicated antidepressant effects of cytokine blockers.
Social Support Prevents Further Distress in Victims of Violence
Researchers found that the inclusion of significant others in cognitive behavioral therapy for victims of violent crimes is beneficial for the victim and indirect victim.
Brain-Derived Neurotrophic Factor: An Effective Biomarker for ECT Response in MDD?
Researchers found no association between depression severity and brain-derived neurotrophic factor (BDNF) levels, and no correlation between BDNF levels and response to electroconvulsive therapy.
Schizophrenia Add-Ons: Beware the Flawed Meta-Analyses Touting Improvements
Clinicians should be discerning when evaluating meta-analyses of schizophrenia add-on therapies such as statins and antidepressants.
Long-Term Lithium Use: More Evidence Needed to Associate With Cancer Risk
The European Medicine Agency has reported that there may be an association between long-term lithium use and reports of both renal tumors and thyroid cancer.
Schizophrenia Therapy Adherence Tied to Patients’ Beliefs
Given the substantial burden of nonadherence to therapy in patients with schizophrenia, new interventions for compliance are critical.
Predicting Poststroke Depression: Biomarkers and Beyond
As depression is one of the most common psychiatric disorders following acute stroke and can be predictive of poor outcomes, identifying biomarkers to recognize the disorder are imperative for improving the clinical course.
Managing Comorbid Opioid and Alcohol Use Disorder
When alcohol and opioid addiction occur together, managing them concomitantly becomes challenging. Whereas some patients may not need medication for alcohol addiction, opioid abuse does require pharmacotherapy.
The Opioid System: The Foundation for Social Risk and Reward
The opioid system is responsible for social pain and reward in the brain; therefore, understanding its underpinnings may help clinicians manage patients with depression and suicidal ideation.
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