Little is known about the long-term outcomes of ketamine infusions for depression. Investigators conducted a retrospective chart review to investigate maintenance intravenous ketamine treatment at Massachusetts General Hospital.
Investigating whether serial ketamine treatments change functional connectivity between limbic structures and resting-state networks.
Among individuals with treatment-resistant depression (TRD), the dissociative side effect of “floating” is not related to an antidepressant response to ketamine and thus cannot be utilized as a predictor of treatment response.
Use of the synaptic plasticity model of therapeutic sleep deprivation has been shown to offer a promising framework for the development of fast-acting treatments for patients with major depressive disorder.
These findings have important implications to mitigate the effect of early-life stress and promote life-course mental health through dealing with childhood intrafamilial aggression and peer bullying experiences.
An analysis to assess the effect of a PGx-guided drug therapy on the length of hospitalization, severity of depression, and number of antidepressant switches.
Patients received 40 Hz gamma tACS to provide data on the use of varying stimulation periods.
In middle-aged and older adults, exposure to repetitive head impacts and traumatic brain injury have been shown to be independently associated with worse depression symptom severity and cognitive functioning.
In women with treatment-resistant major depression, no significant between-group differences were found with the use of adjunctive low-dose transdermal testosterone compared with placebo for antidepressant augmentation.
Can emotional memory retrieval just prior to electroconvulsive therapy sessions improve the outcome of ECT in patients with major depressive disorder?
