Dr. Roger McIntyre suggests that the clinical relevance of cognitive dysfunction for any individual patient can only be adjudicated on a case-by-case basis.
The association between sleep disturbance and inflammation provides support for the possible etiopathogenic role of chronobiological disturbances.
The mixed features specifier identifies a subpopulation that is often misdiagnosed.
Many clinicians have a working assumption that subtyping patients is a critical process relevant to antidepressant treatment selection.
The NIMH has proposed the use of the Research Domain Criteria (RDoC) matrix to identify the neurobiological basis of mental and substance-use disorders.
Clinicians should encourage patients to make lifestyle changes that will favorably impact the body’s inflammatory system.
