Jessica Nye

Investigators adapted a simple compartmental epidemic model to simulate SARS-CoV-2 spread, death, and associated costs in the US in an effort to understand the role of at home testing.

In this study to be presented at the AAN 2021 Virtual Annual Meeting, researchers evaluated the safety and efficacy of lower-sodium oxybate (LXB) in adult participants with idiopathic hypersomnia.

While those with psychological trauma experiences have a poor prognosis with regard to treatment participation and outcomes for substance use disorders, knowledge on the effect of the number of trauma experiences is scarce. In this study the researchers assessed the impact of having experienced multiple potentially traumatic experiences on drug use disorder treatment efficacy.

This study addresses the question of whether prescription opioid medications has a potentially causal role in the risk for depression and anxiety disorder.

The researchers tested whether the COVID-19 pandemic has altered beliefs about the extent to which poverty is caused by external forces and internal dispositions and support for economic inequality.

Deaths by suicide can increase during infectious disease outbreaks. This study analyzed suspected suicide rates in 2020 relative to 2015–19 to assess any early effects of the COVID-19 pandemic in Queensland, Australia.

Childhood ADHD risk was increased among children who were exposed to maternal hypothyroidism during the periconceptual period.

The spectrum of rurality has not been reflected in previous research on rural and urban youth mental health services and does not examine the availability of suicide prevention services. This study used 2 taxonomies of rurality to document the distribution of US mental health facilities that serve youth and offer suicide prevention services.

While previous studies suggest that structural variants (SVs) play an important role in the development and progression of ADHD, these studies focused mostly on those of European ancestry and coding regions. This particular study seeks to address the role of SVs in non-European populations and outside of coding regions.

Before the FDA antidepressant warnings, youth suicide deaths decreased. However, after the warnings and abrupt declines in treatment, this downward trend changed.

Does the stress and anxiety caused by the coronavirus pandemic also extend to body image outcomes?

Despite being common and often comorbid neurodevelopmental disorders, the study found robust yet subtle differences across age groups and the disorders in terms of cortical and subcortical brain structures.

Adverse events, including voluntary psychiatric admission, suicide attempt, serious violent incident, voluntary admission to a general medical ward, overdose of medication or painkillers, were highest among the combined group compared to the monotherapies.

A third of patients presented with an altered mental state, including 9 patients with unspecified encephalopathy, 7 with encephalitis, and 23 fulfilling the clinical definition for psychiatric diagnoses.

The researchers concluded that risk for MCI was associated with neurodegeneration and neuropsychiatric symptoms among adults aged 50 years and older, and that an abnormal FDG-PET was a stronger driving force for cognitive decline.

The researchers concluded that fluoxetine with or without CBT may be the best acute therapy for adolescents with moderate to severe depression, although patients, caregivers, and clinicians should carefully monitor any active intervention.

The researchers concluded that the correlation between interregional cortical thinning during maturation and expression patterns of genes associated with multiple psychiatric disorders suggested a common molecular process.