Furio Pacini

All articles by Furio Pacini

Undifferentiated thyroid cancer

Are you sure the patient has undifferentiated thyroid cancer? Definition Undifferentiated thyroid carcinoma (UTC) refers to a cancer arising from the follicular thyroid epithelium but lacking the typical differentiation features of the thyroid gland: iodine uptake, thyroglobulin secretion, response to thyroid stimulating hormone (TSH) stimulation. These are the most aggressive types of thyroid malignancy. The…

Undifferentiated thyroid cancer

Undifferentiated (Anaplastic) Thyroid Cancer*The original source for this chapter was Prof. Furio Pacini. The chapter was revised for this program by David Gerber, MD. What every physician needs to know: Undifferentiated thyroid carcinoma (UTC) refers to a cancer arising from the follicular thyroid epithelium but lacking the typical differentiation feature of the thyroid gland (iodine…

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