Antidepressants and Bleeding Risk: What’s the Link?
Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.
All articles by DaHee Han, PharmD
Once-Monthly Perseris Approved for the Treatment of Schizophrenia
Perseris, an atypical antipsychotic, has an extended-release delivery system that releases sustained levels of risperidone over 1 month.
Sugary Drinks, Other Added Sugars May Up Risk for Alzheimer Disease
Drinking sugary beverages has been previously linked to markers of preclinical Alzheimer disease, but the risk associated with consuming added sugars is not established.
Cannabinoid Shows Promise for Reducing Agitation, Aggression in Alzheimer Disease
Although treatment with nabilone significantly improved agitation, cognition, and nutrition, the authors cautioned that sedation should be closely monitored.
Intensive Blood Pressure Control Cuts Combined Mild Cognitive Impairment, Dementia Risk
In the previous SPRINT study, researchers compared an intensive BP reduction strategy (target systolic BP <120 mmHg) vs standard BP reduction strategy (target systolic BP <140 mmHg).
Some Statins May Be Associated With Cognition, Memory Deficits
Given the lack of differences seen via the NIS, the authors suggested that subjective questionnaires may not be a trustworthy method to assess possible statin-associated cognitive deficits.
Depression, Apathy Associated With Increased Risk for Mild Cognitive Impairment
Adults with depressive symptoms and apathy in middle and late life were at a higher risk for conversion to mild cognitive impairment (MCI) and dementia.
Effect of ACE Inhibitors on Cognition in Alzheimer Disease Dementia
The genetically-mediated effects of angiotensin-converting enzyme (ACE) inhibitors showed an improvement in cognition in patients with Alzheimer disease dementia but not in functionality.
Aducanumab Beneficial in Cognitive, Functional Scores for Alzheimer Disease
The analysis suggests a beneficial effect of aducanumab on functional and cognitive domain scores in adults with Alzheimer disease.
Cognitive Impairment Profiles Differ Between Parkinson Disease and Alzheimer Disease
As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.
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