How Often Does the FDA Disagree With Its Advisory Committees’ Recommendations?
According to the findings of a recent review, the Food and Drug Administration rarely disagrees with recommendations made by its advisory committees.
All articles by Cassandra Pardini, PharmD
Medications to Treat Cocaine Use Disorder: Are Any Effective?
Although some pharmacological agents may help improve abstinence and treatment retention in patients with cocaine use disorder, the majority of these drugs are ineffective for treating this condition.
Treating MDD in Older Patients: Adverse Effects of Drug Therapy Assessed
Findings of the study revealed that the frequency of adverse events compared with placebo was statistically similar in patients receiving SSRIs but was higher in patients taking SNRIs.
Is Melatonin Beneficial for Pediatric Patients With Sleep Disorders?
A recently published systematic review investigated the benefits and risks of melatonin supplementation for pediatric patients with sleep disturbances.
Case Highlights Potential for Serotonin Syndrome With Single Serotonergic Medication
The patient was instructed to discontinue fluoxetine immediately without tapering and initiate paroxetine 10mg daily the next day, as well as hydroxyzine 50mg twice daily as needed for anxiety.
Nicotine Replacement Products Compared for Smoking Cessation
According to the results of a recent review, the efficacy of nicotine replacement therapy (NRT) in achieving long-term smoking cessation varies based on NRT delivery method, dosage, and timing of initiation.
Plasma Levels of Naloxone Compared Using Various Administration Methods
According to the results of a recently published study, FDANxSpray, the FDA-approved Narcan device for nasal administration, was found to yield higher plasma concentrations of naloxone compared to other devices used to treat opioid overdoses.
Case: Metformin Abuse for Weight Loss Purposes in a Nondiabetic Patient
A recently published report describes the case of a 50-year-old female patient who abused metformin for its weight loss properties, highlighting the importance of clinician awareness of medication abuse and increased patient access to medications via the internet.
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