MRI-based cerebrovascular reactivity is associated with cognitive function independent of Alzheimer disease pathology.
All articles by Amit Akirov, MD
Early sleep fragmentation, estimated by actigraphy, was found to be associated with worse cognitive impairment shortly after critical illness.
Precision medicine offers a promising therapeutic strategy for patients with Parkinson disease, allowing for tailored treatments which reflect the unique pathophysiology in each patient.
High body weight variability may be associated with increased risk for all-cause dementia and Alzheimer dementia in older patients.
Researchers assessed the effect of isradipine on clinical progression in previously untreated patients with early-stage PD.
High-intensity exercise training may improve sleep parameters in patients with Parkinson disease.
Patients with Parkinson disease tend to have an increase in iron content with reduced perfusion in the substantia nigra.
Psychological distress at 3 months after stroke may predict subjective cognitive complaints (SCC) at 12 months after the acute event.
There is no evidence for an association between cerebral β-amyloid deposition, a marker of Alzheimer disease, and intracranial atherosclerotic plaque or stenosis.
Higher flavonol intake through food sources, mostly fruits and vegetables, may protect against the development of Alzheimer disease.
Increased age, male gender, and the presence of baseline cerebral microbleeds is associated with increased risk for developing cerebral microbleeds in any location.
The presence of objective subtle cognitive difficulties (Obj-SCD) on neuropsychological measures may predict faster amyloid accumulation and neurogenerative changes.
Evidence to date suggests that the risk for all-cause dementia is 40% to 60% higher in patients with type 1 or type 2 diabetes.
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