Alzheimer's Disease & Dementia

Prevalence of Alzheimer Disease, Related Dementia Set to Double

Prevalence of Alzheimer Disease, Related Dementia Set to Double

The burden of Alzheimer disease and related dementias (ADRD) is expected to increase to 3.3% in the United States by 2060.

PET imaging of tau may help distinguish Alzheimer Disease from other neurodegenerative disorders

In this cross-sectional study, the tau marker [18F]flortaucipir accurately distinguished Alzheimer Disease dementia from other non-AD neurodegenerative disorders about 90% of the time.

Improved cardiovascular health associated with lower incidence of dementia in older adults

In this prospective cohort study, older patients with more optimal cardiovascular health metrics had a lower rate of developing dementia in a dose-dependent manner.

Increased Levels of Human Herpesvirus Identified in Alzheimer Disease

Increased Levels of Human Herpesvirus Identified in Alzheimer Disease

Participants with Alzheimer disease have increased levels of 2 strains of human herpesvirus.

Herpesvirus Abundant in Alzheimer Disease Brain, New Study Finds

Herpesvirus Abundant in Alzheimer Disease Brain, New Study Finds

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While hundreds of published reports have made an argument for an association between Alzheimer disease and bacteria and viruses, the suggestion of a viral contribution to Alzheimer disease has not always been well received by the greater research community.

Higher Blood Pressure at Midlife Increases Risk for Dementia

Higher Blood Pressure at Midlife Increases Risk for Dementia

The risk of dementia is increased in 50-year-olds with blood pressure ≥130 mm Hg, which is below the current threshold for hypertension.

Anticholinergic Drug Use and Dementia: What's the Link?

Anticholinergic Drug Use and Dementia: What's the Link?

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The use of certain anticholinergic drugs may increase the risk of future dementia.

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Hearing Aids May Mitigate Cognitive Decline, Memory Loss

Using hearing aids may slow cognitive decline in later life.

Dementia Care: Prescribing Trends of Antipsychotics, Mood Stabilizers, and Psychotropic Medications

Dementia Care: Prescribing Trends of Antipsychotics, Mood Stabilizers, and Psychotropic Medications

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Researchers concluded that the partnership did not accelerate the overall decline in antipsychotic medication use among study participants.

Healthy Lifestyle May Protect Against Dementia in Older Adult Carriers of APOE ε4

Healthy Lifestyle May Protect Against Dementia in Older Adult Carriers of APOE ε4

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A study was conducted to assess potential beneficial effects of a lifestyle intervention program on cognition in carriers of the APOE ε4 allele.

Solanezumab does not change cognitive decline in mild Alzheimer’s disease

In patients with mild Alzheimer's disease, solanezumab did not significantly reduce cognitive decline over time.

Positive Beliefs About Age May Protect Older Adults Against Dementia

Positive Beliefs About Age May Protect Older Adults Against Dementia

Positive beliefs about age may protect against dementia.

Symptoms of Apathy Linked With Risk for Dementia in Older Adults

Symptoms of Apathy Linked With Risk for Dementia in Older Adults

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Depressive symptoms and apathy were independently associated with incident dementia in community-dwelling older adults.

Increased Midlife Triglyceride Levels May Be a Modifiable Risk Factor for Alzheimer Disease

Increased Midlife Triglyceride Levels May Be a Modifiable Risk Factor for Alzheimer Disease

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Increased triglyceride levels at midlife are predictive of the presence of β-amyloid 20 years later in cognitively healthy individuals.

Risk for Dementia, Cognitive Decline May Be Linked to Age-Related Hearing Loss

Risk for Dementia, Cognitive Decline May Be Linked to Age-Related Hearing Loss

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There is a greater risk for cognitive decline and impairment in elderly patients who experience age-related hearing loss.

Evaluating Progression of Agitation in Alzheimer's Disease

Evaluating Progression of Agitation in Alzheimer's Disease

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While there has been increasing understanding of Alzheimer's neuropathology, little is known about the relationship between progression of agitation and disease severity.

Alzheimer's Disease Mortality Rate Has Increased 55 Percent

Alzheimer's Disease Mortality Rate Has Increased 55 Percent

The mortality rate from Alzheimer's increased 54.5 percent — from 16.5 per 100,000 people in 1999 to 25.4 per 100,000 in 2014.

Many Patients With Alzheimer's Discontinue AChEIs

Many Patients With Alzheimer's Discontinue AChEIs

More than 81% of participants reported adverse events, but rates were similar between groups.

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