Generic Name and Formulations:
Bisoprolol (as fumarate) 5mg+, 10mg; tabs; +scored.
Indications for ZEBETA:
5mg once daily; max 20mg once daily. Renal or hepatic dysfunction, or bronchospastic disease: initially 2.5mg once daily.
Cardiogenic shock. Overt heart failure. 2nd- or 3rd-degree AV block. Marked sinus bradycardia.
CHF. Angina. Peripheral vascular disease. Asthma. COPD. Surgery. Diabetes. Thyroid disease. Hepatic or renal impairment. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers.
Additive effects with reserpine, guanethidine, other catecholamine depleting drugs, calcium channel blockers, antiarrhythmics, myocardial depressants. Increased rebound hypertension with clonidine withdrawal. Antagonized by rifampin. May block epinephrine.
Headache, fatigue, GI upset, upper respiratory symptoms (eg, cough, dyspnea, rhinitis), chest pain.
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