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TUSSIONEX PENNKINETIC
Cough and cold
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Drug Name:

TUSSIONEX PENNKINETIC CII

Generic Name and Formulations:
Hydrocodone bitartrate 10mg, chlorpheniramine maleate 8mg; per 5mL; as polistirex; ext-rel susp.

Company:
UCB Inc.

Therapeutic Use:

Indications for TUSSIONEX PENNKINETIC:

Cough and upper respiratory symptoms associated with allergy or cold.

Adult:

Use accurate measuring device. ≥12yrs: 5mL every 12hrs; max 10mL/24hrs.

Children:

Use accurate measuring device. <6yrs: see Contraindications. 6–11yrs: 2.5mL every 12hrs; max 5mL/24hrs.

Contraindications:

Children <6yrs of age.

Warnings/Precautions:

Risks from concomitant benzodiazepines or other CNS depressants (see Interactions). Respiratory depression esp. in children; discontinue if occurs. Post-op. Compromised respiratory function (eg, pulmonary disease). Abuse potential (monitor). Head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Underlying intestinal motility disorders. Narrow-angle glaucoma. Asthma. Hypothyroidism. Addison’s disease. Prostatic hypertrophy. Urethral stricture. Severe hepatic or renal impairment. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. May affect or be affected by MAOIs, TCAs. Paralytic ileus may occur with anticholinergics.

Pharmacological Class:

Antitussive + antihistamine.

Adverse Reactions:

Nausea, vomiting, sedation, drowsiness, impairment of mental and physical performance, dysphoria, rash, pruritus; respiratory depression.

How Supplied:

Susp—115mL

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