Substance Use Disorders

Gender Differences in Alcohol Use Disappearing

Gender Differences in Alcohol Use Disappearing

Females are also closing the gender gap with regard to health problems associated with alcohol consumption.

Mechanism of Rapid Antidepressant Effect of Alcohol Elucidated

Mechanism of Rapid Antidepressant Effect of Alcohol Elucidated

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Acute exposure to ethanol led to antidepressant and anxiolytic behaviors in rodents for up to 24 hours.

Reduced Bone Density Among Heavy Users of Cannabis

Reduced Bone Density Among Heavy Users of Cannabis

Researchers find heavy users have lower bone density than cigarette smokers.

Cigarette Smoking Predicts Development of Depression

Cigarette Smoking Predicts Development of Depression

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Cigarette smoking prevalence among persons with severe mental illness is approximately 3 times greater than the rate observed in the general population.

Criticism of 12-Step Groups: Is It Warranted?

Criticism of 12-Step Groups: Is It Warranted?

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One topic of criticism is the relative dearth of scientific evidence regarding the efficacy of 12-step programs.

America's Addiction to Opioids, by Dr. Nora Volkow

Treatment of opioid addiction and preventing overdose deaths

Alcohol Consumption and Alzheimer Disease: A Brief Update

Alcohol Consumption and Alzheimer Disease: A Brief Update

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Basic Research Findings for the Practicing Clinician

The Role of Prescription Opioids in Veterans' Heroin Use

The Role of Prescription Opioids in Veterans' Heroin Use

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Opioid-related disorders are an emerging public health concern globally and in the United States.

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

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These findings are important, as CDC rank alcohol-attributable mortality as the third leading cause of preventable death in the United States.

Cognitive Performance in Patients With Alcohol Use Disorder

Cognitive Performance in Patients With Alcohol Use Disorder

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Researchers assessed social cognition and social problem solving abilities by employing ecologically valid scenario-based tests.

Drug Use in America: New Charts Illustrate Nationwide Trends

Drug Use in America: New Charts Illustrate Nationwide Trends

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The report also sheds light on the most significant predictors of substance abuse.

Synthetic Cannabinoid Drug Poisonings Surge

Synthetic Cannabinoid Drug Poisonings Surge

The increased use of synthetic cannabinoids presents a serious public health threat.

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

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Alterations in reward processing may increase users' risk of continued drug use and subsequent addiction.

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

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Early life trauma interacts with FKBP5 genotype to predict heavy alcohol consumption in college students.

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

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Chronic and severe cannabis-dependence is associated with deficits in striatal dopamine release.

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

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Inhibition of D1 dopamine receptors in medium spiny neurons, or excitation of D1 dopamine receptors in medium spiny neurons, of the striatum, attenuated excessive alcohol consumption in mice.

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

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By taking better care of their health, researchers expect that LINKAGE participants will have better outcomes than usual care participants over time.

Computerized Self-Interview Tool Validated for Substance Abuse Disorder Identification

Computerized Self-Interview Tool Validated for Substance Abuse Disorder Identification

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The ACASI ASSIST has good diagnostic accuracy for detecting unhealthy substance use and substance use disorder for tobacco, alcohol, marijuana, and cocaine use.

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

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Bipolar disorder (BD) is typically characterized by recurrent episodes of mania and depression, but the connection between BD and anxiety needs to be considered.

Arthritis Raises Suicide Risk

Arthritis Raises Suicide Risk

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The findings could have important clinical implications in the treatment of patients with arthritis.

U.S. Medical Schools to Expand Training on Opioid Abuse

U.S. Medical Schools to Expand Training on Opioid Abuse

In 2014, opioids were responsible for nearly 19 000 deaths across the United States.

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

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Marijuana use is associated with development of various neuropsychiatric conditions such as schizophrenia, anxiety, and depression.

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Naloxone is an opioid antagonist that reverses the respiratory depression characteristic of opioid overdose.

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

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Approximately 40% of American college students engage in binge drinking at least once in the past 2 weeks.

Expanded Naloxone Access Could Help Curb Opioid Deaths

Expanded Naloxone Access Could Help Curb Opioid Deaths

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The Role of Psychiatrists as Naloxone Advocates

Opioid Update: Rate of Opioid Misuse Doubles in 10 Years

Opioid Update: Rate of Opioid Misuse Doubles in 10 Years

Nonmedical prescription opioid use among adults in the United States has increased by 161% from 2001-2002 to 2012-2013, while prescription opioid use disorder has increased by 125%.

Long-term Use, Sharing of Prescribed Opioid Medications is Highly Prevalent

Long-term Use, Sharing of Prescribed Opioid Medications is Highly Prevalent

More than 70% of respondents said they gave their spare medications to someone they knew who also struggled with pain.

Microstructure of Ethanol Consumption in Rodent Models of Alcoholism

Microstructure of Ethanol Consumption in Rodent Models of Alcoholism

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Comprehensive measurements of drinking behavior during episodes such as binge, abstinence, and relapse are essential to reveal the factors and mechanisms that underlie alcohol abuse and dependence.

Declining Marijuana Use, Conduct Problems Among Adolescents

Declining Marijuana Use, Conduct Problems Among Adolescents

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Cannabis use disorder (CUD) is currently the most widely reported illegal substance use disorder.

CDC: E-cigarette Smoking Rates Up Among U.S. Adolescents

CDC: E-cigarette Smoking Rates Up Among U.S. Adolescents

The rate of cigarette smoking and premarital sex is down, however, as is soda consumption and illegal use of prescription drugs.

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