Substance Use Disorder

Substance Use Disorders in Autism Revisited

Substance Use Disorders in Autism Revisited

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Autism is a heritable neurodevelopmental disorder that is approximately 4 times more prevalent in males than females.

Global Burden of Disease Study 2015: Drug Abuse and Alzheimer Disease

Global Burden of Disease Study 2015: Drug Abuse and Alzheimer Disease

In America, deaths associated with opioid use increased more than five-fold over the past 25 years.

Alcohol Use Disorder Drug Shows Promise

Alcohol Use Disorder Drug Shows Promise

CDC rank alcohol-attributable mortality as the third leading cause of preventable death in the United States.

FDA Starts App Competition To Help Reduce Overdose Mortality

FDA Starts App Competition To Help Reduce Overdose Mortality

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No application is currently available to connect carriers of naloxone with nearby opioid overdose victims.

Rise in Heroin Use and Prescription Opioid Abuse

Rise in Heroin Use and Prescription Opioid Abuse

Both medical and non-medical use of prescription opioid medications is associated with a higher risk for transitioning to heroin use.

Criticism of 12-Step Groups: Is It Warranted?

Criticism of 12-Step Groups: Is It Warranted?

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One topic of criticism is the relative dearth of scientific evidence regarding the efficacy of 12-step programs.

EEG Findings Indicate Surprising Trajectory of Cocaine Craving in Early Recovery

EEG Findings Indicate Surprising Trajectory of Cocaine Craving in Early Recovery

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According to the most recent available data, 14% of Americans have tried cocaine, and 0.6% (1.5 million individuals aged 12 or older) had used it in the past month.

America's Addiction to Opioids, by Dr. Nora Volkow

Treatment of opioid addiction and preventing overdose deaths

Marijuana Use and Abuse, 2002-2014

Marijuana Use and Abuse, 2002-2014

Fewer people believe marijuana is harmful.

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

Female-specific CBT for Women Diagnosed With Alcohol Use Disorder

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Compared with men, women diagnosed with AUD have higher rates of premature death due to alcohol abuse.

Alcohol Consumption and Alzheimer Disease: A Brief Update

Alcohol Consumption and Alzheimer Disease: A Brief Update

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Basic Research Findings for the Practicing Clinician

The Abuse Potential of Modafinil

The Abuse Potential of Modafinil

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In order clarify the abuse potential of modafinil, investigators characterized its psychostimulant profile by using mice.

The Role of Prescription Opioids in Veterans' Heroin Use

The Role of Prescription Opioids in Veterans' Heroin Use

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Opioid-related disorders are an emerging public health concern globally and in the United States.

THC Causes Cognitive Indolence in Rats

THC Causes Cognitive Indolence in Rats

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Δ9-Tetrahydrocannabinol (THC) is the main psychoactive chemical ingredient in cannabis.

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

Childhood ADHD and Adulthood Alcohol Problems: The Role of Emotional Impulsivity

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These findings are important, as CDC rank alcohol-attributable mortality as the third leading cause of preventable death in the United States.

Cognitive Performance in Patients With Alcohol Use Disorder

Cognitive Performance in Patients With Alcohol Use Disorder

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Researchers assessed social cognition and social problem solving abilities by employing ecologically valid scenario-based tests.

Drug Use in America: New Charts Illustrate Nationwide Trends

Drug Use in America: New Charts Illustrate Nationwide Trends

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The report also sheds light on the most significant predictors of substance abuse.

Synthetic Cannabinoid Drug Poisonings Surge

Synthetic Cannabinoid Drug Poisonings Surge

The increased use of synthetic cannabinoids presents a serious public health threat.

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

Long-term Marijuana Use Associated with Dampened Nucleus Accumbens Reward Response

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Alterations in reward processing may increase users' risk of continued drug use and subsequent addiction.

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

Interactive Effects of Genotype and Childhood Adversity on Alcohol Consumption

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Early life trauma interacts with FKBP5 genotype to predict heavy alcohol consumption in college students.

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

Severe Cannabis Dependence and Blunted Striatal Dopamine Release: A Comorbidity Independent Effect

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Chronic and severe cannabis-dependence is associated with deficits in striatal dopamine release.

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

Striatal D1 and D2 Dopamine Receptor Activity Exert Opposite Influences on Alcohol Drinking

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Inhibition of D1 dopamine receptors in medium spiny neurons, or excitation of D1 dopamine receptors in medium spiny neurons, of the striatum, attenuated excessive alcohol consumption in mice.

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

LINKAGE Trial Ups Health Care Engagement In Addiction Treatment Patients

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By taking better care of their health, researchers expect that LINKAGE participants will have better outcomes than usual care participants over time.

Computerized Self-Interview Tool Validated for Substance Abuse Disorder Identification

Computerized Self-Interview Tool Validated for Substance Abuse Disorder Identification

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The ACASI ASSIST has good diagnostic accuracy for detecting unhealthy substance use and substance use disorder for tobacco, alcohol, marijuana, and cocaine use.

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

Following an Episode of Mania, Adults With Bipolar Disorder at Equal Risk for Depression or Anxiety

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Bipolar disorder (BD) is typically characterized by recurrent episodes of mania and depression, but the connection between BD and anxiety needs to be considered.

Arthritis Raises Suicide Risk

Arthritis Raises Suicide Risk

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The findings could have important clinical implications in the treatment of patients with arthritis.

U.S. Medical Schools to Expand Training on Opioid Abuse

U.S. Medical Schools to Expand Training on Opioid Abuse

In 2014, opioids were responsible for nearly 19 000 deaths across the United States.

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

Marijuana Hair Testing: An Accurate Method for Detecting Consumption?

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Marijuana use is associated with development of various neuropsychiatric conditions such as schizophrenia, anxiety, and depression.

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Naloxone is an opioid antagonist that reverses the respiratory depression characteristic of opioid overdose.

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

"Drunkorexia" Linked To Both Eating and Substance Use Disorders

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Approximately 40% of American college students engage in binge drinking at least once in the past 2 weeks.

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