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SINOGRAFIN
Imaging agents
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Drug Name:

SINOGRAFIN Rx

Generic Name and Formulations:
Diatrizoate meglumine 527mg, iodipamide meglumine 268mg; per mL; soln for intrauterine instillation; contains sodium 0.91mg/mL, organically bound iodine 380mg/mL.

Company:
Bracco Diagnostics

Therapeutic Use:

Indications for SINOGRAFIN:

Hysterosalpingography.

Adult:

See literature for information on administration and radiography. Empty bladder before exam. 3–4mL administered in fractional doses of approx. 1mL are usually adequate to visualize the uterus; an additional 3–4mL will demonstrate the tubes. Total doses of 1.5–10mL have been used.

Children:

Not established.

Contraindications:

Pregnancy. During menstrual period. External genitalia or genital tract infection. Within 30 days of curettage or conization or within 6 months following termination of pregnancy.

Warnings/Precautions:

Should be performed by personnel trained in diagnostic procedures that involve radiopaque diagnostic agents. Carcinoma of the uterus and/or uterine/tubes; possible dispersion of carcinogenic cells during procedure. History of asthma/allergy. Nursing mothers.

Interactions:

May interfere with thyroid tests.

Pharmacological Class:

Radiopaque contrast medium.

Adverse Reactions:

Dizziness, syncope, hypotension, chills, fever, nausea, vomiting, abdominal pain and tenderness, hypersensitivity reactions; rare: bradycardia, hypotension, cardiac arrest, death.

How Supplied:

Single-dose vial (10mL)—10

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