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SHINGRIX
Vaccines
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Drug Name:

SHINGRIX Rx

Generic Name and Formulations:
Varicella zoster vaccine recombinant, adjuvanted; susp for IM inj after reconstitution (contains 50mcg of recombinant glycoprotein E antigen, 50mcg of monophosphoryl lipid A, and 50mcg of QS-21); per 0.5mL; preservative-free.

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for SHINGRIX:

Prevention of herpes zoster (shingles) in adults ≥50yrs of age.

Limitations Of use:

Not for preventing primary varicella infection (chickenpox).

Adult:

<50yrs: not recommended. Give by IM inj in deltoid region of upper arm. ≥50yrs: one 0.5mL dose at Month 0 followed by second dose anytime between 2–6 months later. Administer immediately upon reconstitution or store refrigerated and use within 6hrs.

Children:

<18yrs: not established.

Contraindications:

Allergies to any previous Shingrix vaccination.

Warnings/Precautions:

Review immunization history prior to administration. Have appropriate medical treatment and supervision available to manage allergic reactions. Pregnancy. Nursing mothers.

Interactions:

Immunosuppressants may reduce efficacy of Shingrix. Concomitant inactivated influenza vaccines: see full labeling.

Pharmacological Class:

Shingles vaccine.

Adverse Reactions:

Local reactions (eg, pain, redness, swelling), myalgia, fatigue, headache, shivering, fever, GI symptoms.

Note:

To report adverse events, contact VAERS at (800) 822-7967.

Generic Availability:

NO

How Supplied:

Single-dose vials—1, 10 (antigen + adjuvant components)

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