Schizophrenia

Predictors of Optimal Schizophrenia Outcomes Using PP1M, PP3M Treatment

Predictors of Optimal Schizophrenia Outcomes Using PP1M, PP3M Treatment

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Researchers sought to examine the most efficacious treatment for clinical remission in adults with schizophrenia.

Cariprazine Effective for Long-Term Sustained Remission in Patients with Schizophrenia

Cariprazine Effective for Long-Term Sustained Remission in Patients with Schizophrenia

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Cariprazine treatment is associated with significantly higher rates of long-term sustained remission in patients with schizophrenia.

High Serum Concentrations of Second-Generation Antipsychotics in Elderly

High Serum Concentrations of Second-Generation Antipsychotics in Elderly

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Serum concentrations of second-generation antipsychotics were significantly higher in patients over the age of 70.

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

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Switching therapy to Aristada resulted in statistically significant and clinically meaningful improvement in schizophrenia symptoms.

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

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Adding telmisartan to treatment with olanzapine or clozapine may improve symptoms of schizophrenia.

Why Do Antipsychotics Cause Weight Gain?

Why Do Antipsychotics Cause Weight Gain?

Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.

Shared Decision Making in Psychiatry:  An Effective Practice Strategy

Shared Decision Making in Psychiatry: An Effective Practice Strategy

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Shared decision making encourages a clinical partnership that can result in optimal treatment outcomes.

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

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Long-term treatment of schizophrenia with cariprazine was found to be both safe and well-tolerated.

FDA Approves Austedo for Treatment of Tardive Dyskinesia

FDA Approves Austedo for Treatment of Tardive Dyskinesia

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The FDA has approved Austedo.

Psychosis Not Associated With Bipolar Disorder Severity

Psychosis Not Associated With Bipolar Disorder Severity

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Psychosis in patients with bipolar disorder was not associated with worse clinical or functional outcomes.

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

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Children and adolescent offspring of patients with schizophrenia demonstrate more attenuated psychotic symptoms.

Liraglutide Improves Cardiometabolic Disturbances in Schizophrenia Tx With Clozapine

Liraglutide Improves Cardiometabolic Disturbances in Schizophrenia Tx With Clozapine

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Glucose tolerance and body mass index in patients with schizophrenia were improved by liraglutide.

Antipsychotic Drug Side Effects More Frequent With Intellectual Disability

Antipsychotic Drug Side Effects More Frequent With Intellectual Disability

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UK researchers evaluated extrapyramidal side effects of antipsychotic medication in patients with and without intellectual disability.

Negative Symptoms In Schizophrenia Reduced By Novel Therapy

Negative Symptoms In Schizophrenia Reduced By Novel Therapy

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Patients with schizophrenia in the MIN-101 trial demonstrated lower negative factor scores than a placebo group.

Memory Training Opportunities Exist for Patients With Schizophrenia

Memory Training Opportunities Exist for Patients With Schizophrenia

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Impaired recollection could be a vulnerability marker for schizophrenia, whereas impaired social context memory could be a disease-related marker.

Long-acting Antipsychotics: Better Efficacy in Some Outcomes for Schizophrenia

Long-acting Antipsychotics: Better Efficacy in Some Outcomes for Schizophrenia

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Schizophrenia treatment with long-acting injectable antipsychotic agents resulted in lower rehospitalization rates.

Surprise Babies Are More Common Than You Think

Surprise Babies Are More Common Than You Think

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Unknown pregnancies and surprise babies are more common than people think.

Results for Patients With Schizophrenia Who Transition to PP3M

Results for Patients With Schizophrenia Who Transition to PP3M

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A high percentage of patients were persistent and adherent to their PP3M treatment.

Clozapine as Causal Agent in Gastrointestinal Hypomotility Events

Clozapine as Causal Agent in Gastrointestinal Hypomotility Events

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Clozapine-induced gastrointestinal hypomotility is a medical emergency that requires urgent attention.

Clozapine Protects Patients With Tx-resistant Schizophrenia Against Self-harm

Clozapine Protects Patients With Tx-resistant Schizophrenia Against Self-harm

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Clozapine might lower risk of self-harm for patients with treatment-resistant schizophrenia.

Mental Illness Leads to Higher Prevalence of Blood Viruses

Mental Illness Leads to Higher Prevalence of Blood Viruses

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HIV, hepatitis B and hepatitis C are more common among patients with mental illnesses.

Childhood Maltreatment Associated With Increased Risk of Psychosis in Ultra-High Risk Individuals

Childhood Maltreatment Associated With Increased Risk of Psychosis in Ultra-High Risk Individuals

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Child maltreatment is significantly more prevalent in young individuals who present with UHR symptoms compared with controls.

Increases in Autonomic Function May Predict Auditory Hallucinations in SCZ

Increases in Autonomic Function May Predict Auditory Hallucinations in SCZ

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Increases in autonomic function may predict the occurrence and severity of auditory hallucinations in patients with schizophrenia, suggesting a regulation of these experiences by the autonomic nervous system.

Antipsychotics Have Few Negative Long-term Effects on Schizophrenia Outcomes

Antipsychotics Have Few Negative Long-term Effects on Schizophrenia Outcomes

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The positive effects of antipsychotic medications in patients with schizophrenia and other psychotic disorders outweigh the adverse effects of antipsychotics on long-term outcomes.

Late Teen Emotional Stability Inversely Tied to Mental Illness

Late Teen Emotional Stability Inversely Tied to Mental Illness

Emotional stability assessed in late adolescence is inversely associated with serious mental illness.

Metabolic, Endocrine Profiles Examined in Long-term Schizophrenia Therapy

Metabolic, Endocrine Profiles Examined in Long-term Schizophrenia Therapy

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Schizophrenia outpatients were examined in this 52-week open-label extension trial.

Antipsychotic Symptoms Persist for Patients Seeking Treatment

Antipsychotic Symptoms Persist for Patients Seeking Treatment

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Dopamine-blocking antipsychotics are ineffective right from the onset of illness.

Antipsychotic Side Effect Treatment Gets FDA Approval

Antipsychotic Side Effect Treatment Gets FDA Approval

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Ingrezza significantly and rapidly improved tardive dyskinesia symptoms compared to placebo, rmarking a tremendous breakthrough for patients suffering from TD.

Bipolar Disorder, Schizophrenia, and Cardiometabolic Comorbidities Lead to Greater Mortality

Bipolar Disorder, Schizophrenia, and Cardiometabolic Comorbidities Lead to Greater Mortality

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Schizophrenia, mood disorders, and diabetes were among the top 20 conditions with the highest all-cause 30-day readmission rates.

Schizophrenia Symptom Improvements and Adverse Effects

Schizophrenia Symptom Improvements and Adverse Effects

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Participants in the risperidone group were generally more likely to achieve a significant clinical improvement in their mental state.

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