Schizophrenia

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

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Patients with schizophrenia-spectrum disorders had higher odds of being aggressive than people with bipolar disorder with a recent manic episode.

Neuropsychiatric Symptoms Occur More Frequently in Relatives of Patients With ALS

Neuropsychiatric Symptoms Occur More Frequently in Relatives of Patients With ALS

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Family members of ALS patients have higher rates of neuropsychiatric conditions.

Readmission Risk for Schizophrenia Associated With Younger Age

Readmission Risk for Schizophrenia Associated With Younger Age

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For patients with schizophrenia or schizoaffective disorder, younger age was significantly associated with an increased rate of readmission.

Decrease in Atypical Antipsychotics in Children Following Peer Review Policy Implementation

Decrease in Atypical Antipsychotics in Children Following Peer Review Policy Implementation

The use of atypical antipsychotics can be reduced with the implementation of a peer review prior authorization policy.

Risk of Schizophrenia May Be Impacted by Inflammatory Biomarkers

Risk of Schizophrenia May Be Impacted by Inflammatory Biomarkers

The risk of developing schizophrenia may be impacted by specific inflammatory biomarkers.

Transcranial Stimulation Reduces Auditory Hallucinations in Schizophrenia

Transcranial Stimulation Reduces Auditory Hallucinations in Schizophrenia

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Transcranial direct current stimulation might aid patients with schizophrenia who experience auditory hallucinations.

Lurasidone Reduces Agitation in Acute Exacerbation of Schizophrenia

Lurasidone Reduces Agitation in Acute Exacerbation of Schizophrenia

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Lurasidone reduced agitation in patients with acute exacerbation of schizophrenia.

People With Schizophrenia More Likely to Die at a Younger Age

People With Schizophrenia More Likely to Die at a Younger Age

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People with schizophrenia have a mortality rate 3 times higher than the general population, which may be linked to higher rates of smoking, alcohol consumption, poor diet, and lack of exercise in people with schizophrenia.

Quality of Diabetes Care Low Among Patients With Schizophrenia

Quality of Diabetes Care Low Among Patients With Schizophrenia

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The quality of diabetes care was examined in patients with and without schizophrenia in a Danish nationwide cohort.

Long-Acting Injectable Antipsychotics Delay Schizophrenia Relapse

Long-Acting Injectable Antipsychotics Delay Schizophrenia Relapse

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In patients with schizophrenia, long-acting injectable formulations of paliperidone palmitate delay relapse significantly after withdrawal.

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

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Dopamine dysfunction underlies the pathoetiology of psychosis in both bipolar disorder and schizophrenia.

Predictors of Development of Early Onset Psychosis in Parkinson Disease

Predictors of Development of Early Onset Psychosis in Parkinson Disease

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Researchers conducted a prospective case-control study to examine predictors of early and late-onset psychosis in Parkinson disease.

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

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These findings suggest that there are critical periods of development associated with a higher risk of persistent negative symptoms.

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

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In this study, 672 patients with schizophrenia were evaluated with the EPICOG-SCH brief cognitive battery.

Signs of Schizophrenia That Should Not Be Ignored

Signs of Schizophrenia That Should Not Be Ignored

Seven signs and symptoms might alert someone to the possible presentation of schizophrenia.

Secondary Outcome Bias Prevalent in Antipsychotic Randomized Controlled Trials

Secondary Outcome Bias Prevalent in Antipsychotic Randomized Controlled Trials

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Understanding more about the original protocols of RCTs for various drugs may offer helpful insights into the clinical implications of those trials' findings.

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

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The FDA issued a refusal to file letter for a new drug application.

Predictors of Optimal Schizophrenia Outcomes Using PP1M, PP3M Treatment

Predictors of Optimal Schizophrenia Outcomes Using PP1M, PP3M Treatment

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Researchers sought to examine the most efficacious treatment for clinical remission in adults with schizophrenia.

Cariprazine Effective for Long-Term Sustained Remission in Patients With Schizophrenia

Cariprazine Effective for Long-Term Sustained Remission in Patients With Schizophrenia

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Cariprazine treatment is associated with significantly higher rates of long-term sustained remission in patients with schizophrenia.

High Serum Concentrations of Second-Generation Antipsychotics in Elderly

High Serum Concentrations of Second-Generation Antipsychotics in Elderly

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Serum concentrations of second-generation antipsychotics were significantly higher in patients over the age of 70.

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

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Switching therapy to Aristada resulted in statistically significant and clinically meaningful improvement in schizophrenia symptoms.

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

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Adding telmisartan to treatment with olanzapine or clozapine may improve symptoms of schizophrenia.

Why Do Antipsychotics Cause Weight Gain?

Why Do Antipsychotics Cause Weight Gain?

Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.

Shared Decision Making in Psychiatry:  An Effective Practice Strategy

Shared Decision Making in Psychiatry: An Effective Practice Strategy

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Shared decision making encourages a clinical partnership that can result in optimal treatment outcomes.

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

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Long-term treatment of schizophrenia with cariprazine was found to be both safe and well-tolerated.

FDA Approves Austedo for Treatment of Tardive Dyskinesia

FDA Approves Austedo for Treatment of Tardive Dyskinesia

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The FDA has approved Austedo.

Psychosis Not Associated With Bipolar Disorder Severity

Psychosis Not Associated With Bipolar Disorder Severity

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Psychosis in patients with bipolar disorder was not associated with worse clinical or functional outcomes.

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

Increased Psychotic Symptoms in Offspring of Patients With Schizophrenia

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Children and adolescent offspring of patients with schizophrenia demonstrate more attenuated psychotic symptoms.

Liraglutide Improves Cardiometabolic Disturbances in Schizophrenia Tx With Clozapine

Liraglutide Improves Cardiometabolic Disturbances in Schizophrenia Tx With Clozapine

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Glucose tolerance and body mass index in patients with schizophrenia were improved by liraglutide.

Antipsychotic Drug Side Effects More Frequent With Intellectual Disability

Antipsychotic Drug Side Effects More Frequent With Intellectual Disability

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UK researchers evaluated extrapyramidal side effects of antipsychotic medication in patients with and without intellectual disability.

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