Schizophrenia and Psychoses

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Secondary Outcome Bias Prevalent in Antipsychotic Randomized Controlled Trials

Secondary Outcome Bias Prevalent in Antipsychotic Randomized Controlled Trials

Understanding more about the original protocols of RCTs for various drugs may offer helpful insights into the clinical implications of those trials' findings.

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Predictors of Development of Early Onset Psychosis in Parkinson Disease

Predictors of Development of Early Onset Psychosis in Parkinson Disease

Researchers conducted a prospective case-control study to examine predictors of early and late-onset psychosis in Parkinson disease.

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

These findings suggest that there are critical periods of development associated with a higher risk of persistent negative symptoms.

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

In this study, 672 patients with schizophrenia were evaluated with the EPICOG-SCH brief cognitive battery.

Signs of Schizophrenia That Should Not Be Ignored

Signs of Schizophrenia That Should Not Be Ignored

Seven signs and symptoms might alert someone to the possible presentation of schizophrenia.

Diabetes Risk for Children, Young Adults on Second-Generation Antipsychotics

Diabetes Risk for Children, Young Adults on Second-Generation Antipsychotics

Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

The FDA issued a refusal to file letter for a new drug application.

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

Paliperidone Inadequate Responders May Benefit from Switch to Aripiprazole Lauroxil ER

Switching therapy to Aristada resulted in statistically significant and clinically meaningful improvement in schizophrenia symptoms.

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

Adjunctive Telmisartan's Effects on Symptoms of Schizophrenia

Adding telmisartan to treatment with olanzapine or clozapine may improve symptoms of schizophrenia.

Why Do Antipsychotics Cause Weight Gain?

Why Do Antipsychotics Cause Weight Gain?

Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

Long-Term Cariprazine Safe, Tolerable for Schizophrenia

Long-term treatment of schizophrenia with cariprazine was found to be both safe and well-tolerated.

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