Research on monogenic disorders has made vital contributions to all aspects of medical care, including our understanding of pain pathophysiology.
The NIH is awarding more than 100 new grants to over 170 researchers at 60 institutions that will total more than $70 million.
You have probably heard the term 'Big Data' being bandied around, but what does it actually mean for the psychiatry sector? Dr Nicola Davies explains what Big Data is, before exploring how it's currently being applied within psychiatry.
The increased use of synthetic cannabinoids presents a serious public health threat.
The combination of behavioral and cognitive therapy approaches with medications is likely the most effective intervention for adults diagnosed with severe obsessive-compulsive disorder.
Alterations in reward processing may increase users' risk of continued drug use and subsequent addiction.
New findings underline the potential importance of signaling pathways in the striatum for understanding bipolar disorder pathophysiology.
Early life trauma interacts with FKBP5 genotype to predict heavy alcohol consumption in college students.
Chronic and severe cannabis-dependence is associated with deficits in striatal dopamine release.
In terms of depressive and negative symptoms, in the present meta-analysis, researchers estimate that 1 in 9 patients with schizophrenia will improve with add-on antidepressants.
Inhibition of D1 dopamine receptors in medium spiny neurons, or excitation of D1 dopamine receptors in medium spiny neurons, of the striatum, attenuated excessive alcohol consumption in mice.
The accuracy of the PHQ-2 in identifying major depression is lower than originally thought.
As the Congress, VA, CDC and the Obama Administration address the issue, recent neuroimaging studies point to effective diagnostic tools available for PTSD and TBI — two common conditions among suicide victims.
Neuroimaging studies have shown several neurophysiological substrates for depression: An overview by Theodore Henderson, MD, PhD.
Augmentation and combination approaches with pharmaceuticals are often used in clinical practice.
Pharmacological and optogenetic inhibition of ventral pallidum neurons during cue presentation impedes reward-seeking behavior.
New platform helps clinicians bridge the gap in translation of knowledge from bench to bedside.