Psychosis

Significant Cognitive Impairment in Those At High Risk of Psychosis

Significant Cognitive Impairment in Those At High Risk of Psychosis

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Studying cognition deficits during the clinical high risk period allows researchers to observe cognitive defects before chronicity and long-term medication use obscure the core deficits.

Low Levels of Vitamin D in Patients With Bipolar Disorder

Low Levels of Vitamin D in Patients With Bipolar Disorder

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Approximately 2.5% of people worldwide are estimated to have bipolar spectrum disorders, which are a significant cause of neuropsychiatric disability.

Delusions in Schizophrenia Associated With Myelin Abnormalities, Neuroinflammation

Delusions in Schizophrenia Associated With Myelin Abnormalities, Neuroinflammation

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Study provides further evidence for the effects of white matter fiber abnormalities and neuroinflammation on positive symptoms in patients with schizophrenia.

White Matter Abnormalities and Clinical Symptom Severity in Schizophrenia

White Matter Abnormalities and Clinical Symptom Severity in Schizophrenia

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New findings provide an insight about the association between white matter microstructure and the severity of schizophrenia clinical symptoms.

Neuroimaging of Schizophrenia: The Importance of Illness Severity and Duration

Neuroimaging of Schizophrenia: The Importance of Illness Severity and Duration

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Researchers used voxel-based morphometry, which allows examination on a voxel-wise basis across the whole brain, to assess whether structural abnormalities in schizophrenia are static or progressive.

Neuroinflammation in Schizophrenia: New PET Brain Imaging Studies

Neuroinflammation in Schizophrenia: New PET Brain Imaging Studies

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TSPO expression is frequently used as a biomarker for brain inflammation during PET imaging.

Cannabinoid Receptor System Dysregulation in Schizophrenia

Cannabinoid Receptor System Dysregulation in Schizophrenia

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Researchers explored the role of the dysregulated cannabinoid receptor system in patients diagnosed with schizophrenia.

Novel Candidate Biomarker Identified for Schizophrenia

Novel Candidate Biomarker Identified for Schizophrenia

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Whereas the expression levels of CDK4 and MCM7 were significantly decreased only in the acute state, POLD4 was significantly decreased in the acute and remission states in the patients diagnosed with schizophrenia.

Common Meds Increase Hospitalization for Dehydration, Heat-Linked Illness

Common Meds Increase Hospitalization for Dehydration, Heat-Linked Illness

Commonly used medications have been linked to an increased risk of hospitalization for dehydration and heat-related illness.

Prevalence of Antipsychotic Polypharmacy at 12%

Prevalence of Antipsychotic Polypharmacy at 12%

A diagnosis of schizophrenia and a length of stay of 90 days or more are the strongest predictors of polypharmacy.

Smoking Reduction Linked to Reduced Suicidality in Patients With Psychotic Conditions

Smoking Reduction Linked to Reduced Suicidality in Patients With Psychotic Conditions

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At 12 months, researchers found a significant association between smoking reduction and suicidality.

Aberrant Reward Processing Likely Precedes Psychotic Disorders

Aberrant Reward Processing Likely Precedes Psychotic Disorders

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Genetic risk for psychosis influences reward processing in healthy adolescents.

Exposure to Stressful Triggers Increases Risk for Violent Criminality Irrespective of Psychiatric Condition

Exposure to Stressful Triggers Increases Risk for Violent Criminality Irrespective of Psychiatric Condition

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The largest 7-day absolute risk of criminal violence was observed after exposure to violence in patients diagnosed with schizophrenia, bipolar disorder, as well as in unaffected individuals.

FDA Warning: Antipsychotic Linked to Impulse-Control Problems

FDA Warning: Antipsychotic Linked to Impulse-Control Problems

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The FDA has mandated new warnings to include a list of compulsive behaviors.

Which Came First, the Cigarette or the Psychiatric Diagnosis?

Which Came First, the Cigarette or the Psychiatric Diagnosis?

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University of Washington Tobacco Scholar Joseph Cerimele, MD, MPH, discusses the relationship between smoking and psychiatric illness.

Frequency of Suicidal Ideation Predicts Suicide Attempts But Not Deaths

Frequency of Suicidal Ideation Predicts Suicide Attempts But Not Deaths

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Persistent suicidal ideation was identified in up to 40% of participants with first-episode psychosis.

Ambient Noise May Exacerbate Cognitive Deficits in Schizophrenia

Ambient Noise May Exacerbate Cognitive Deficits in Schizophrenia

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Reducing exposure to environmental noise may provide cognitive benefit in individuals with schizophrenia.

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