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Phentolamine
Hypertension
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Drug Name:

Phentolamine Rx

Generic Name and Formulations:
Phentolamine mesylate 5mg/vial; for IM or IV inj after reconstitution; contains mannitol.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Phentolamine:

Hypertensive episodes in patients with pheochromocytoma.

Adult:

Pre-op: 5mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 5mg IV as needed. See literature.

Children:

Pre-op: 1mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 1mg IV as needed. See literature.

Contraindications:

MI or history of MI. Coronary insufficiency. Angina. Coronary artery disease.

Warnings/Precautions:

Arrhythmias. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Avoid concomitant cardiac glycosides.

Pharmacological Class:

Alpha adrenergic blocker.

Adverse Reactions:

Cerebrovascular spasms or occlusion, MI, tachycardia, arrhythmias, hypotension, weakness, dizziness, flushing, nasal congestion, GI disturbances.

Note:

Formerly known under the brand name Regitine.

How Supplied:

Vial—1

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