Pain

Clinical Hypnosis May Be Effective for Cancer Pain, IBS, Headaches

Clinical Hypnosis May Be Effective for Cancer Pain, IBS, Headaches

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Results of brain imaging studies demonstrate that "hypnosis influences all of the cortical areas and neurophysiological processes that underlie pain and emotions."

Migraine Intensity Affects Muscle Pain in Major Depressive Disorder

Migraine Intensity Affects Muscle Pain in Major Depressive Disorder

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Migraine was more significantly associated with muscle soreness or pain than anxiety disorders in patients with MDD.

Neural Entrainment Through Visual, Auditory Stimulation Reduces Pain Perception

Neural Entrainment Through Visual, Auditory Stimulation Reduces Pain Perception

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Patients in the visual arm of the study wore flashing LED goggles delivering visual stimulation in the alpha-band range.

Cognitive Processes' Influence on Pain Perception

Cognitive Processes' Influence on Pain Perception

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Evidence indicates that distraction can provide pain relief, highlighting the influence cognitive processes have on pain perception.

Issues With Clinical Trials That Impede New Pain Drug Development

Issues With Clinical Trials That Impede New Pain Drug Development

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The major issues of drug development are that pre-clinical animal efficacy studies do not accurately predict human efficacy, and clinical trials often inaccurately fail to show drug efficacy.

Advancing Pain Management: Human Studies

Advancing Pain Management: Human Studies

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Research on monogenic disorders has made vital contributions to all aspects of medical care, including our understanding of pain pathophysiology.

Medication Overuse Headache: Diagnosis & Treatment

Medication Overuse Headache: Diagnosis & Treatment

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The recovery time varies depending on which class of medication the patient is overusing.

Predicting Placebo Response May Now be Possible

Predicting Placebo Response May Now be Possible

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Connectivity in the right midfrontal gyrus may help predict placebo response. This finding has widespread implications in drug development.

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

Crystal Structure of Cannabinoid Receptor 1 Determined: Implications for Managing Pain

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The crystal structure may provide inspiration for designing drugs that refine efficacy and avoid adverse events.

Pain Sensitivity Can Be Socially Transmitted Via Olfactory Cues

Pain Sensitivity Can Be Socially Transmitted Via Olfactory Cues

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The transfer of hyperalgesia is mediated by olfactory cues in mice, shedding light on the role of social and environmental cues in pain pathogenesis.

Patients with Medically Unexplained Pain Stigmatized, Socially Excluded

Patients with Medically Unexplained Pain Stigmatized, Socially Excluded

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Patients with chronic pain often report feeling isolated and misunderstood, or that others believe they are exaggerating their pain or somehow using it to their benefit.

Open-Label Placebo Treatment Reduces Chronic Pain

Open-Label Placebo Treatment Reduces Chronic Pain

Even when knowing they were taking a placebo, patients still obtained relief from pain.

CDC Guidelines on Opioids: Reaction from the American Academy of Pain Management

CDC Guidelines on Opioids: Reaction from the American Academy of Pain Management

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Dr Twillman, Executive Director for the American Academy of Pain Management, emphasizes the fact that CDC guidelines on opioids are expert- and not evidence-based.

Non-opioid Drugs and Methods for Pain Control

Non-opioid Drugs and Methods for Pain Control

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Treating acute pain before it develops into chronic pain may be the key to preventing chronic pain from arising in the first place.

Listing Kratom As Schedule I Will Impede Research Opportunities

Listing Kratom As Schedule I Will Impede Research Opportunities

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The DEA's plan to list kratom as a Schedule I controlled substance would make researching the possible opioid substitute much more difficult.

Relationship Between Depression and Stable Angina Outcomes

Relationship Between Depression and Stable Angina Outcomes

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The strongest predictor of depression in patients with chronic stable angina was an episode of depression within the past 10 years.

The Relation of Traumatic Stress to Pain Severity, Mood Disorders

The Relation of Traumatic Stress to Pain Severity, Mood Disorders

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Individuals with a history of abuse experience higher levels of pain, anxiety, and depression.

Novel Opioids for Pain Relief

Novel Opioids for Pain Relief

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Researchers discovered novel opioid analgesics, displaying reduced respiratory depression.

Comorbid Chronic Pain and Depression: Gene x Environment Interaction

Comorbid Chronic Pain and Depression: Gene x Environment Interaction

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Genetic factors and the environment patients share with their partner or spouse may determine their risk of developing chronic pain and help explain the association between chronic pain and depression.

The Microbiome and Stress: Relevance to Irritable Bowel Syndrome

The Microbiome and Stress: Relevance to Irritable Bowel Syndrome

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An estimated 20-60% of patients with irritable bowel syndrome (IBS) have comorbid anxiety and/or depression.

The Importance of Pain Psychology Curricula in Training and Education

The Importance of Pain Psychology Curricula in Training and Education

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Dr Darnall suggests that psychosocial factors are some of the most powerful determinants of pain outcomes.

Arthritis Raises Suicide Risk

Arthritis Raises Suicide Risk

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The findings could have important clinical implications in the treatment of patients with arthritis.

The Long-Term Mental Health Outcomes of Adolescent Chronic Pain

The Long-Term Mental Health Outcomes of Adolescent Chronic Pain

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Adolescents who experience chronic pain have higher prevalence of anxiety and depressive symptoms in adulthood.

Novel Clinical Application of Optogenetics: Migraine Headaches

Novel Clinical Application of Optogenetics: Migraine Headaches

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Optogenetic tools enable light-based modulation of genetically defined neurons and temporally precise stimulation of neural circuit activity.

Mood Disorders in a Chronic Pain Population

Mood Disorders in a Chronic Pain Population

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The Need For a Better Screening Tool

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Coprescribing Naloxone Helps Reduce Unintentional Opioid Overdose

Naloxone is an opioid antagonist that reverses the respiratory depression characteristic of opioid overdose.

CBT in Individuals With Rheumatoid Arthritis for Managing Chronic Pain

CBT in Individuals With Rheumatoid Arthritis for Managing Chronic Pain

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In an email interview with Rheumatology Advisor, Louise Sharpe, PhD, spoke about the practical ramifications of her research for clinicians who treat rheumatoid arthritis.

Cognitive Alterations in a Growing Population of Cancer Survivors

Cognitive Alterations in a Growing Population of Cancer Survivors

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Cognitive Profile and Putative Mechanisms of Cancer Therapy-Associated Cognitive Changes: A Primer for Mental Health Professionals

FDA Approves Innovative Sustained-Release Drug Implant to Control Addiction

FDA Approves Innovative Sustained-Release Drug Implant to Control Addiction

FDA approves innovative sustained-release drug delivery implant to control opioid dependence for up to 6 months.

Importance of Perceived Control in Treating Pain, Depression

Importance of Perceived Control in Treating Pain, Depression

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Clinicians should focus on treating patients' pain and psychological conditions together.

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