Opioid-Related Disorder

Long-acting buprenorphine depot injections may be efficacious in treatment of opioid use disorder

Weekly or monthly buprenorphine depot injections were non-inferior to daily sublingual buprenorphine/naloxone in maintaining no evidence of illicit opioid use at 24 weeks in outpatients with opioid use disorder.

Unit-dose packaging of buprenorphine-naloxone associated with reduced pediatric unintentional exposures

Pediatric unintentional opioid exposures decreased by more than 75% following the introduction of child-resistant unit-dose packaging.

First Nonopioid Drug Approved for Managing Opioid Withdrawal Symptoms

First Nonopioid Drug Approved for Managing Opioid Withdrawal Symptoms

By

Lucemyra, a selective alpha 2-adrenergic receptor agonist, works by reducing the release of norepinephrine and decreasing sympathetic tone.

Opioid-Related Payments Linked to Increase in Opioid Rx

Opioid-Related Payments Linked to Increase in Opioid Rx

Receipt of opioid-related payments from industry in 2014 was associated with increased opioid prescribing in 2015.

Sources of Misused Opioids in Older Adults

Sources of Misused Opioids in Older Adults

By

Recent physician-prescribed opioids represent the main source of provenance of the drug in individuals age ≥65 years who misuse them.

Contribution of Synthetic Opioids to Drug Overdose Deaths

Contribution of Synthetic Opioids to Drug Overdose Deaths

By

Opioids were the leading contributor to drug overdose deaths between 2015 and 2016.

Prenatal Exposure to Opiates, Illicit Substances Associated With ADHD, Autism in Offspring

Prenatal Exposure to Opiates, Illicit Substances Associated With ADHD, Autism in Offspring

By

The results of this study suggest that children prenatally exposed to substances should receive early mental health assessment.

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

How the City of San Francisco Is Tackling the Intertwined HIV/HCV and Opioid Epidemics

By

Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.

Talk therapy, modified for literacy level, helps ease chronic pain for disadvantaged populations

Both modified cognitive behavioral therapy (CBT) and pain education (EDU) interventions were associated with improved pain in patients with disadvantaged backgrounds.

Significant variation in mortality trends in substance use disorders among US counties

Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014. Mortality rates for drug use disorders increased both nationally and in each county over the same period.

Little Packaging Information on Storage, Disposal of Opioid Pain-Relievers

Little Packaging Information on Storage, Disposal of Opioid Pain-Relievers

By

Package inserts of opioid analgesics may not consistently provide information regarding safe drug storage and/or disposal.

Treatment Duration of Extended-Release Naltrexone for Opioid Dependence and Outcomes

Treatment Duration of Extended-Release Naltrexone for Opioid Dependence and Outcomes

By

A longer duration of extended-release naltrexone treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse.

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By County

By

Researchers calculated age-standardized mortality rates on a county level in the United States between 1980 and 2014, specifically examining rates for self-harm, interpersonal violence, alcohol use, and drug use.

Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?

Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?

By

While results so far may seem to support a link between increased access to cannabis and a reduction in prescription opioid use, findings from a study published in 2018 found otherwise.

Pharmacotherapy Improves Criminal Justice Outcomes in Opioid Dependence With Mental Illness

Pharmacotherapy Improves Criminal Justice Outcomes in Opioid Dependence With Mental Illness

By

All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.

Antidepressant Adherence Associated With Cessation of Long-term Prescription Opioid Use

Antidepressant Adherence Associated With Cessation of Long-term Prescription Opioid Use

Antidepressant medication adherence is linked with cessation of opioid use.

Presence of Prescription Opioids May Increase Risk of Initiation in Household Members

Presence of Prescription Opioids May Increase Risk of Initiation in Household Members

By

Prescription opioids kept in the household may increase the risk for opioid initiation in co-residents.

Risk for Neonatal Abstinence Syndrome: Methadone vs Buprenorphine During Pregnancy

Risk for Neonatal Abstinence Syndrome: Methadone vs Buprenorphine During Pregnancy

By

Methadone exposure in utero was shown to have an increased risk of neonatal abstinence syndrome compared with buprenorphine.

FDA Approval: Once-Monthly Buprenorphine Injection for Opioid Use Disorder

FDA Approval: Once-Monthly Buprenorphine Injection for Opioid Use Disorder

By

The FDA has announced the approval of Sublocade for the treatment of moderate to severe opioid use disorder.

Clinton Foundation: Recommendations to Address the Opioid Epidemic

Clinton Foundation: Recommendations to Address the Opioid Epidemic

By

The Clinton Foundation's Health Matters Initiative, in partnership with the Johns Hopkins Bloomberg School of Public Health, issued a report providing 49 recommendations under 10 topic areas on how to address the opioid crisis.

Low Opioid Use in Veterans With Recent Traumatic Brain Injury

Low Opioid Use in Veterans With Recent Traumatic Brain Injury

By

Veterans diagnosed with TBI don't use opioids very often.

Virtual Reality May Offer Solution to Opioid Crisis

Virtual Reality May Offer Solution to Opioid Crisis

By

Virtual reality may help combat the opioid crisis.

APA: Americans Believe Treatment, Not Punishment, Best for Opioid Crisis

APA: Americans Believe Treatment, Not Punishment, Best for Opioid Crisis

A poll found 58% in favor of prioritizing access to treatment; 26% in favor of more punishment.

Opioid Prescription: Concerns With New CDC Guidelines

Opioid Prescription: Concerns With New CDC Guidelines

By

Jeffrey Fudin, PharmD, discusses concerns he has regarding the CDC guideline for prescribing opioids for chronic pain.

Opioid Management and Difficult Patients

Opioid Management and Difficult Patients

By

Anthony Mariano, PhD, offered advice to clinicians for tapering patients off opioids.

Identifying Patients Who Need Higher Methadone Doses

Identifying Patients Who Need Higher Methadone Doses

By

Polymorphism at the level of drug receptors, transporters, or other proteins involved in drug metabolism or action may dampen a drug's efficacy or increase its toxicity.

Opioid Use Growing Among Pregnant Women

Opioid Use Growing Among Pregnant Women

By

The increase in cases of neonatal abstinence syndrome corresponds with the reported rise in opioid use during pregnancy.

Naltrexone-Assisted Detox vs Buprenorphine Taper for Opioid Dependence

Naltrexone-Assisted Detox vs Buprenorphine Taper for Opioid Dependence

By

Researchers compared 2 treatment methods in 150 individuals seeking outpatient treatment for prescription opioid or heroin dependence.

Opioid Overdoses a Leading Cause of Death in Rural Areas

Opioid Overdoses a Leading Cause of Death in Rural Areas

Factors including economics, environment, and demographic and social factors might put rural residents at a higher risk of these preventable causes of death.

Uncovering Undiagnosed HIV in Heterosexuals: Examining Behavioral Intervention

Uncovering Undiagnosed HIV in Heterosexuals: Examining Behavioral Intervention

By

Barriers to HIV testing include distrust of medical settings, fear of HIV stigma, and substance use problems.

Sign Up for Free e-newsletters