Weekly or monthly buprenorphine depot injections were non-inferior to daily sublingual buprenorphine/naloxone in maintaining no evidence of illicit opioid use at 24 weeks in outpatients with opioid use disorder.
Unit-dose packaging of buprenorphine-naloxone associated with reduced pediatric unintentional exposuresMay 22, 2018
Pediatric unintentional opioid exposures decreased by more than 75% following the introduction of child-resistant unit-dose packaging.
Lucemyra, a selective alpha 2-adrenergic receptor agonist, works by reducing the release of norepinephrine and decreasing sympathetic tone.
Receipt of opioid-related payments from industry in 2014 was associated with increased opioid prescribing in 2015.
Recent physician-prescribed opioids represent the main source of provenance of the drug in individuals age ≥65 years who misuse them.
Opioids were the leading contributor to drug overdose deaths between 2015 and 2016.
The results of this study suggest that children prenatally exposed to substances should receive early mental health assessment.
Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.
Both modified cognitive behavioral therapy (CBT) and pain education (EDU) interventions were associated with improved pain in patients with disadvantaged backgrounds.
Mortality rates decreased for alcohol use disorders, self-harm, and interpersonal violence between 1980 and 2014. Mortality rates for drug use disorders increased both nationally and in each county over the same period.
Package inserts of opioid analgesics may not consistently provide information regarding safe drug storage and/or disposal.
A longer duration of extended-release naltrexone treatment in individuals with opioid dependence was associated with improved outcomes and reduced rates of relapse.
Researchers calculated age-standardized mortality rates on a county level in the United States between 1980 and 2014, specifically examining rates for self-harm, interpersonal violence, alcohol use, and drug use.
While results so far may seem to support a link between increased access to cannabis and a reduction in prescription opioid use, findings from a study published in 2018 found otherwise.
All 3 opioid-dependence pharmacotherapies — methadone, buprenorphine, and oral naltrexone — were associated with reductions in inpatient substance abuse treatment.
Antidepressant medication adherence is linked with cessation of opioid use.
Prescription opioids kept in the household may increase the risk for opioid initiation in co-residents.
Methadone exposure in utero was shown to have an increased risk of neonatal abstinence syndrome compared with buprenorphine.
The FDA has announced the approval of Sublocade for the treatment of moderate to severe opioid use disorder.
The Clinton Foundation's Health Matters Initiative, in partnership with the Johns Hopkins Bloomberg School of Public Health, issued a report providing 49 recommendations under 10 topic areas on how to address the opioid crisis.
Veterans diagnosed with TBI don't use opioids very often.
Virtual reality may help combat the opioid crisis.
A poll found 58% in favor of prioritizing access to treatment; 26% in favor of more punishment.
Jeffrey Fudin, PharmD, discusses concerns he has regarding the CDC guideline for prescribing opioids for chronic pain.
Anthony Mariano, PhD, offered advice to clinicians for tapering patients off opioids.
Polymorphism at the level of drug receptors, transporters, or other proteins involved in drug metabolism or action may dampen a drug's efficacy or increase its toxicity.
The increase in cases of neonatal abstinence syndrome corresponds with the reported rise in opioid use during pregnancy.
Researchers compared 2 treatment methods in 150 individuals seeking outpatient treatment for prescription opioid or heroin dependence.
Factors including economics, environment, and demographic and social factors might put rural residents at a higher risk of these preventable causes of death.
Barriers to HIV testing include distrust of medical settings, fear of HIV stigma, and substance use problems.
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