Physical Activity Tied to Fewer Symptoms in Kids with Multiple Sclerosis

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Physical Activity Tied to Fewer Symptoms in Kids with Multiple Sclerosis
Physical Activity Tied to Fewer Symptoms in Kids with Multiple Sclerosis

HealthDay News -- For children with multiple sclerosis, those reporting greater amounts of physical activity have fewer symptoms, according to a study in Neurology.

Stephanie A. Grover, from the University of Toronto, and colleagues conducted a cross-sectional study to examine the correlation between physical activity and multiple sclerosis (MS) disease activity, depression, and fatigue. The study involved 110 patients (79 with monophasic acquired demyelinating syndrome [mono-ADS] and 31 with MS).

The researchers found that, compared with patients with mono-ADS, patients with MS reported less strenuous (P=0.002) and total (P=0.0291) physical activity. For patients with MS, reporting greater amounts of moderate physical activity metabolic equivalents correlated with fewer sleep/rest fatigue symptoms.

There was a correlation noted between participation in strenuous physical activity and smaller T2 lesion volumes and lower annualized relapse rate. Total brain volume was not associated with participation in physical activity.

"Children with MS reporting higher levels of strenuous physical activity had lower T2 lesion volumes and lower relapse rates, suggesting a potential protective effect of strenuous physical activity in this population," the researchers wrote. "Further longitudinal studies are needed to establish the relationship of physical activity to MS symptoms and disease activity in this population."

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

References

  1. Grover SA et al. Neurology. 2015; doi:10.1212/WNL.0000000000001939.

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