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MYOBLOC
Muscle spasms
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Drug Name:

MYOBLOC Rx

Generic Name and Formulations:
Rimabotulinumtoxin B 2500 Units/0.5mL, 5000 Units/1mL, 10000 Units/2mL; soln for IM inj; contains human albumin; preservative-free.

Company:
Solstice Neurosciences

Therapeutic Use:

Indications for MYOBLOC:

Cervical dystonia, to reduce severity of abnormal head position and neck pain.

Adult:

Should be administered and managed by experienced physicians. Individualize. Treatment-experienced: Initially 2500 to 5000 Units divided among affected muscles. Treatment-naïve: use lower initial dose. Adjust subsequent doses based on response.

Children:

Not recommended.

Contraindications:

Infection at proposed injection site.

Warnings/Precautions:

Not interchangeable with other botulinum toxin products. Pre-existing dysphagia. Respiratory disorders. Neuromuscular disorders (eg, myasthenia gravis, ALS, Lambert-Eaton syndrome); monitor closely. Contains human albumin; monitor for possible viral disease transmission. Pregnancy (Cat.C). Nursing mothers.

Interactions:

May be potentiated by aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds). Concomitant other botulinum toxin products may potentiate neuromuscular paralysis.

Pharmacological Class:

Neuromuscular blocker.

Adverse Reactions:

Inj site reactions, dry mouth, dysphagia (may be severe), dyspepsia, headache, respiratory difficulties, allergic reactions (discontinue if occurs), spread of toxin effect (may be fatal).

How Supplied:

Single-use vial—1

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