Mood Disorders

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

Asenapine Prevents Recurrence of Mood Events in Bipolar Disorder

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Asenapine decreases the time to recurrence of manic and depressive episodes among patients with bipolar I disorder.

Psychosocial Intervention Improves Early Adherence to Antidepressants

Psychosocial Intervention Improves Early Adherence to Antidepressants

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Early adherence is an especially problematic, significant and modifiable barrier to quality care for depression.

Lithium Reduces Risk of Suicide in Patients With Mood Disorders

Lithium Reduces Risk of Suicide in Patients With Mood Disorders

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Lithium is the only medication to demonstrate an antisuicidal effect over and above its action on mood episodes in bipolar disorder.

Risk of Anxiety Disorder Relapse After Discontinuing Antidepressants

Risk of Anxiety Disorder Relapse After Discontinuing Antidepressants

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Researchers examined whether the risk of relapse or time to relapse was related to type of anxiety disorder, duration of previous treatment, and other factors.

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

Examining Rates of Conversion From Unipolar Depression to Bipolar Disorder

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Making mental health predictions based on clinical presentation has major limitations.

Why Do Antipsychotics Cause Weight Gain?

Why Do Antipsychotics Cause Weight Gain?

Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.

Pharmacologic Approach to Disruptive Mood Dysregulation Disorder in Children

Pharmacologic Approach to Disruptive Mood Dysregulation Disorder in Children

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Combination treatment may provide relief from the distinctive symptoms of severe, recurrent temper outbursts and persistent irritability.

Anxiety and Depression's Effect on BMD in Anorexia

Anxiety and Depression's Effect on BMD in Anorexia

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Scores for both anxiety and depression are associated with low BMD.

Depression, Anxiety May Affect Bone Metabolism in Young Adults

Depression, Anxiety May Affect Bone Metabolism in Young Adults

In young adults, MDD, GAD, and SSRI use is associated with bone metabolism.

Off-Label Use of Ketamine for the Treatment of Patients With Mood Disorders

Off-Label Use of Ketamine for the Treatment of Patients With Mood Disorders

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Ketamine dosing continues to raise safety concerns.

Risk of Mood Disorders Increased From Sugary Beverages, Foods

Risk of Mood Disorders Increased From Sugary Beverages, Foods

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The risk for mood disorders increases with the more sugar consumed from beverages and food.

Treating Perinatal Mood Disorders: Web-Based Interventions Effective?

Treating Perinatal Mood Disorders: Web-Based Interventions Effective?

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A significant improvement in depressive symptoms was measured using validated rating scales.

Most Opioids Prescribed for Patients With Mental Health Disorders

Most Opioids Prescribed for Patients With Mental Health Disorders

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Of the estimated 38.6 million patients who have a mental health disorder, 7.2 million of them use prescription opioids

Psychiatric Disorders in Children Linked to Celiac Disease

Psychiatric Disorders in Children Linked to Celiac Disease

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Children with celiac disease are at a 1.4-fold increased risk for psychiatric disorders.

Are Mood Disorders Conditions of Premature Aging?

Are Mood Disorders Conditions of Premature Aging?

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John Kane, MD, considers prevention and treatment approaches for mood disorders.

Mood Disorder Treatment With Ketamine Requires Patient Selection

Mood Disorder Treatment With Ketamine Requires Patient Selection

Available data on ketamine use are limited and risks should be considered before its use.

Antidepressant Side Effects More Common with Comorbid Panic Disorder

Antidepressant Side Effects More Common with Comorbid Panic Disorder

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Therapeutic response to antidepressants is highly variable, which may be partially due to associated side effects.

Assessing Internet-Based Depression Prevention in Chronic Back Pain

Assessing Internet-Based Depression Prevention in Chronic Back Pain

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Methods to prevent depression could help reduce the disease burden for both affected persons and society.

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

Increased Risk of PTSD in Parents of Kids With Critical Heart Defects

The researchers proposed integrating mental health screening and treatment into pediatric cardiology care.

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

Rapid Increase in Opioid Dose Increases Risk of New-Onset Depression

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Dose escalation may be a proxy for loss of control or undetected abuse known to be associated with depression.

Depression Often Untreated in Dialysis Patients

Depression Often Untreated in Dialysis Patients

Many dialysis patients also do not wish to receive aggressive treatment for their depression.

Which Antidepressants May Cause Birth Defects?

Which Antidepressants May Cause Birth Defects?

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Anything that has the potential to disturb the serotonin signaling process has the potential to result in a wide variety of malformations.

Preschoolers With Depression Show Reduced Response to Rewards

Preschoolers With Depression Show Reduced Response to Rewards

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Altered reward sensitivity may be an indicator of depression in preschool-aged children.

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

Aging a Stronger Predictor of Depression, Negative Mood Than Menopause

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Women in the menopausal transition and early postmenopause are at higher risk for depressive symptoms and negative mood than those in late postmenopause.

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

Youth Depression Onset Predicted by Anxiety, Family History, Adversity

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Fear and anxiety showed the strongest correlation with development of major depression in children.

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Pilots Suffer Depression, Suicidal Thoughts at Fairly High Rates

Hundreds of active pilots manage depressive symptoms without the possibility of treatment due to fear of negative career impact.

Switching Antidepressants During Nonresponse May Be Ineffective

Switching Antidepressants During Nonresponse May Be Ineffective

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There is no conclusive benefit to switching to a new antidepressant during nonresponse.

Depressive Symptoms in AMD, Diabetic Retinopathy Reduced

Depressive Symptoms in AMD, Diabetic Retinopathy Reduced

Self-care tools can reduce depressive symptoms in patients with age-related macular degeneration (AMD) or diabetic retinopathy (DR).

16% of US Adults Report Psychiatric Drug Use

16% of US Adults Report Psychiatric Drug Use

1 in 6 US adults take a psychiatric medication to treat conditions such as depression, anxiety, and insomnia.

Psychoeducation No More Effective Than Peer Support at Reducing Time to Next Bipolar Episode

Psychoeducation No More Effective Than Peer Support at Reducing Time to Next Bipolar Episode

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Group psychoeducation is a low-cost psychological intervention with specific clinical benefits in early bipolar disorder, if the focus of care is preventing future mania relapse and improving self-management, interpersonal function, and support.

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