Mood Disorders

Psychiatric Comorbidities Increase Neurologic Disability in Multiple Sclerosis

Psychiatric Comorbidities Increase Neurologic Disability in Multiple Sclerosis

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Patients with MS and comorbid psychiatric conditions have increased severity of subsequent neurological disability.

Collaborative care intervention does not improve health in chronic heart failure, but alleviates depression and fatigue

Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA), a collaborative care intervention combining symptom and psychosocial care, did not improve heart failure-specific health status in chronic heart disease compared with usual care. When compared with usual care, CASA did improve secondary outcomes of depression and fatigue.

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

Personality Functioning Associated With Global Functioning in Bipolar Disorder I

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These results highlight the potential utility of incorporating personality functioning assessments into bipolar disorder I treatment plans to fully restore global functioning during remission.

Prenatal SSRI Exposure Associated With Fetal Neurodevelopmental Changes

Prenatal SSRI Exposure Associated With Fetal Neurodevelopmental Changes

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These data indicate a potential association between prenatal SSRI exposure and the development of the fetal amygdala-insula circuit, possibly via anomalous serotonin signaling.

Increased Prevalence of Depression, Anxiety After Colorectal Cancer

Increased Prevalence of Depression, Anxiety After Colorectal Cancer

The prevalence of depression and anxiety are increased among survivors of colorectal cancer.

Psychiatric Illness, Not Antidepressants, Associated With Breast Milk Insufficiency

Psychiatric Illness, Not Antidepressants, Associated With Breast Milk Insufficiency

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Mothers struggling with depression may benefit from additional breastfeeding education and support.

Children With Autism, ADHD at Increased Risk for Anxiety, Mood Disorders

Children With Autism, ADHD at Increased Risk for Anxiety, Mood Disorders

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Recognizing the increased risk for mood disorders in children with ASD and ADHD may be useful for clinicians and parents in developing proper screening and treatment strategies.

Clinical Outcomes Assessed for Major Depressive Disorder With Psychotic Features

Clinical Outcomes Assessed for Major Depressive Disorder With Psychotic Features

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Major depressive disorder with psychotic features had comparative long-term outcomes with schizophrenia, schizoaffective disorder, and bipolar disorder.

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

GDF-15 Levels: Examining Premature Aging in Bipolar Disorder

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Researchers noted that therapeutic interventions focused on GDF-15 levels may decrease mortality risk and increase longevity in patients with bipolar disorder.

Mood Disorders Up for Children of Consanguineous Parents

Mood Disorders Up for Children of Consanguineous Parents

Children of first-cousin consanguineous parents have increased odds of mental health issues and needing antidepressant medications.

Adolescent Anxiety, Depression Risks Not Directly Associated With Perinatal HIV Status

Adolescent Anxiety, Depression Risks Not Directly Associated With Perinatal HIV Status

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Investigators assessed the prevalence and risk factors associated with symptoms of anxiety and depression in adolescents with HIV and those without infection but affected by HIV.

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

Family-Focused Intervention Effective for Caregivers of Patients With Bipolar Disorder

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Patients associated with caregivers who received family-focused treatment also demonstrated a significant decrease in depressive symptoms compared with patients associated with caregivers in the control group.

Antidepressant Types Linked to Different Adverse Outcomes in Adults With Depression

Antidepressant Types Linked to Different Adverse Outcomes in Adults With Depression

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Selective serotonin reuptake inhibitors and other antidepressants, such as tricyclic antidepressants, are associated with increased adverse outcomes in patients aged 20 to 64 years diagnosed with depression.

Psychiatric, Somatic Comorbidities Common in Hidradenitis Suppurativa

Psychiatric, Somatic Comorbidities Common in Hidradenitis Suppurativa

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Among the somatic comorbidities evaluated were acne, type 1 diabetes, Down syndrome, hypertension, inflammatory bowel diseases, inflammatory joint diseases, metabolic syndrome, obesity, pilonidal sinus, and thyroid disorders.

Stopping Exercise Found to Increase Depressive Symptoms

Stopping Exercise Found to Increase Depressive Symptoms

Ceasing regular exercise increases depressive symptoms, particularly in women.

Depression-Associated Stigma May Limit Access to Chronic Pain Care

Depression-Associated Stigma May Limit Access to Chronic Pain Care

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Individuals with chronic pain and comorbid depression may experience higher levels of stigma related to their conditions compared with patients with chronic pain alone.

Untreated Depression Common in Women of Childbearing Age

Untreated Depression Common in Women of Childbearing Age

Many non-pregnant women of childbearing age are suffering from untreated depression.

Incidence of Psychiatric Disorders in Rheumatoid Arthritis

Incidence of Psychiatric Disorders in Rheumatoid Arthritis

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The incidence and prevalence of psychiatric disorders such as depression, anxiety, and bipolar disorder are higher in the rheumatoid arthritis population.

Comorbid Mood Disorders and Neuropathic Pain: Exploring the Connections

Comorbid Mood Disorders and Neuropathic Pain: Exploring the Connections

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Neuropathic pain has been linked with negative outcomes including psychological distress.

Manic Switching After Light Therapy Historically Low in Bipolar Disorder

Manic Switching After Light Therapy Historically Low in Bipolar Disorder

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These findings challenge existing concerns about the association of light therapy with manic switching and may be useful for clinicians in developing treatment strategies for patients with bipolar disorder.

Updated Guidelines for Identifying, Managing Depression in Adolescents

Updated Guidelines for Identifying, Managing Depression in Adolescents

Practice guidelines have been updated to assist primary care physicians in the screening and treatment of adolescent depression.

Early Menarche Linked to Antisocial Behavior, Depression That Persists Into Adulthood

Early Menarche Linked to Antisocial Behavior, Depression That Persists Into Adulthood

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These results indicated a persistence of depressive and antisocial symptoms and related behavioral patterns far beyond what has been demonstrated in prior research.

Quality of Life May Be Improved in Chronic Pain With Multidisciplinary Social Cognitive Intervention

Quality of Life May Be Improved in Chronic Pain With Multidisciplinary Social Cognitive Intervention

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Social cognitive intervention may lead to improvements in health-related QoL in patients with chronic pain.

Treatment Initiation for Depression Suboptimal in Primary Care

Treatment Initiation for Depression Suboptimal in Primary Care

Treatment initiation for depression is suboptimal in the primary care setting despite availability.

Cranial electrical stimulation may be of modest benefit for treating depression and anxiety

Low-strength evidence suggests that cranial electrical stimulation (CES) may be moderately beneficial for patients with depression and anxiety. There was insufficient evidence that CES provides clinically important benefit for fibromyalgia, neuromusculoskeletal pain, degenerative joint pain, headache, depression, or insomnia.

Antidepressants More Effective Than Placebo for Acute Depression in Adults

Antidepressants More Effective Than Placebo for Acute Depression in Adults

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By bringing together published and unpublished data from more than 500 double-blind, randomized, controlled trials, this study represents the best currently available evidence base to guide the choice of pharmacologic treatment for adults with acute depression.

Effects of Depression, Alcohol Use on Retention in Antiretroviral Therapy

Effects of Depression, Alcohol Use on Retention in Antiretroviral Therapy

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Alcohol use disorder and depression were both associated with higher disengagement from antiretroviral therapy for patients with HIV.

Probing the Link Between Mood Disorders and Lithium in Water Supplies

Probing the Link Between Mood Disorders and Lithium in Water Supplies

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Michael Thase, MD, comments on the potential for lithium in drinking water as a psychiatric prophylactic agent.

Third Trimester Maternal SSRI Exposure Linked to Depression, Anxiety in Offspring

Third Trimester Maternal SSRI Exposure Linked to Depression, Anxiety in Offspring

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The issue of whether and how prenatal SSRI exposure affects offspring has remained murky.

Dermatologists May Need Further Training in Identifying Depression

Dermatologists May Need Further Training in Identifying Depression

Fair to poor concordance was seen between dermatologist assessment and patient self-reporting.

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