Mood Disorders

Sodium Valproate May Lower Amygdala Volume in Pediatric Bipolar Disorder

Sodium Valproate May Lower Amygdala Volume in Pediatric Bipolar Disorder

By

Studies conducted in animals and adults have indicated that sodium valproate may have neuroprotective and neurotrophic effects, but the effects of sodium valproate on brain structure in pediatric bipolar disorder are not known.

Lipophilic Statins Not Associated With Significant Increase in Risk for Depression

Lipophilic Statins Not Associated With Significant Increase in Risk for Depression

By

Research has suggested a number of possible relationships with lipophilic statins, including a protective phenomenon against depression and higher risk for dementia, although these associations remain controversial.Research has suggested a number of possible relationships with lipophilic statins, including a protective phenomenon against depression and higher risk for dementia, although these associations remain controversial.

Fatigue a Potential Indicator of Overlapping Sleep Apnea and COPD

Fatigue a Potential Indicator of Overlapping Sleep Apnea and COPD

By

On the basis of these findings, researchers recommended that "[f]atigue should be evaluated whenever there is clinical suspicion of overlap syndrome."

Novel Parent-Child Interaction Therapy Targets Preschool-Aged Depression

Novel Parent-Child Interaction Therapy Targets Preschool-Aged Depression

By

Children in the waiting list group exhibited significantly worse impairments on the Preschool Feelings Checklist at the study's end, but children who completed the therapy showed improvements in emotion regulation and guilt processing.

Distinct Characteristics in Children at Risk for Schizophrenia vs Bipolar Disorder

Distinct Characteristics in Children at Risk for Schizophrenia vs Bipolar Disorder

By

The findings of this study contribute to the understanding of the neurodevelopmental cognitive vulnerability in middle childhood for the children of people with either schizophrenia or bipolar disorder.

Midlife Fitness Associated With Lower Risk for Depression and CVD Death

Midlife Fitness Associated With Lower Risk for Depression and CVD Death

By

These results demonstrate the importance of midlife fitness to prevent depression and subsequent CVD mortality in older age.

Depression, Anxiety May Correlate With Disease Activity in Early Rheumatoid Arthritis

Depression, Anxiety May Correlate With Disease Activity in Early Rheumatoid Arthritis

By

This research provides further support to compelling data linking inflammation and depression.

Remission of Treatment-Resistant Depression in Veterans Depends on Close Clinical Observation

Remission of Treatment-Resistant Depression in Veterans Depends on Close Clinical Observation

By

This study supports the effects of close clinical observation and the use of combined treatment interventions including repetitive transcranial magnetic stimulation for achieving remission in veterans with treatment-resistant depression.

Depression Associated With Balance Impairments in Multiple Sclerosis

Depression Associated With Balance Impairments in Multiple Sclerosis

By

Investigators note that depression should be evaluated and treated in patients with multiple sclerosis and may hinder balance rehabilitation.

Executive Function Impairment in Unipolar vs Bipolar Depression

Executive Function Impairment in Unipolar vs Bipolar Depression

By

These results suggest that executive function impairments may be similar in patients with unipolar and bipolar depression.

Increased Suicide Risk in Cardiovascular Disease With Highest Rates in Younger Patients

Increased Suicide Risk in Cardiovascular Disease With Highest Rates in Younger Patients

By

Patients with these cardiovascular diseases would benefit from early psychiatric help.

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

Managing Comorbid Migraine and Mood Disorders: A Synergistic Approach

By

People with migraines and comorbid mood disorders often need treatments that address both conditions, as well as management of sleep, stress, and lifestyle issues.

Cannabis Associated With Poorer Symptom Course in Anxiety, Mood Disorders

Cannabis Associated With Poorer Symptom Course in Anxiety, Mood Disorders

By

These data may be useful to clinicians in gaining insight on the potential risks of cannabis use among their patients with anxiety or mood disorders.

Technology-Enhanced Intervention in the ED Appears Promising for Reducing Underage Drinking, Consequences

Technology-Enhanced Intervention in the ED Appears Promising for Reducing Underage Drinking, Consequences

By

This intervention provides flexibility in the clinical setting, allowing for therapist delivery when staff is available and computer delivery when staff resources are not available.

Once-Monthly Aripiprazole Effective as Maintenance Treatment for Bipolar I Disorder

Once-Monthly Aripiprazole Effective as Maintenance Treatment for Bipolar I Disorder

By

These data demonstrate the efficacy and safety of AOM 400 in long-term maintenance treatment of bipolar I disorder and support its broader use in the medical field.

Brexpiprazole Effective as Adjunct Therapy in Major Depressive Disorder

Brexpiprazole Effective as Adjunct Therapy in Major Depressive Disorder

By

Clinicians may find these data useful in treating patients with major depressive disorder and an inadequate response to antidepressant treatment alone.

Negative Social Media Interactions Have Significant Effects on Depressive Symptoms

Negative Social Media Interactions Have Significant Effects on Depressive Symptoms

By

It may be important to increase awareness of avoiding negative social media encounters to reduce the risk for depressive symptoms.

No Evidence Found That Efavirenz Use Increases Depression in HIV Antiretroviral Therapy

No Evidence Found That Efavirenz Use Increases Depression in HIV Antiretroviral Therapy

By

The researchers believe this study is the first to detect a statistically significant, unexpected inverse association between efavirenz use and depression.

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

By

These findings are in line with previous research, which suggested that abuse and neglect in childhood have different effects on the brain.

Older Age Associated With Worse Major Depressive Disorder Outcomes

Older Age Associated With Worse Major Depressive Disorder Outcomes

By

The age association remained significant after additional adjustments for clinical and social factors such as loneliness and pain. As such, age-specific factors cannot alone explain the poorer MDD course associated with older age.

Women With Epilepsy More Likely to Have Major Depressive Disorder

Women With Epilepsy More Likely to Have Major Depressive Disorder

By

Investigators sought to determine the frequency of major depressive disorder in patients in epilepsy clinics.

Medications with depression as a possible adverse effect associated with increased depression risk

This association suggests that it may be beneficial for practitioners to have increased awareness of depression as a possible adverse effect of medications.

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

By

As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.

Cognitive Performance, Mood Deficits, White Matter Hyperintensities in Migraine

Cognitive Performance, Mood Deficits, White Matter Hyperintensities in Migraine

By

Carefully assessing cognitive performance using a screening test to detect visuospatial/executive, attention, and memory dysfunction in patients with migraine.

Medications With Adverse Effect of Depression Are Commonly Used

Medications With Adverse Effect of Depression Are Commonly Used

An estimated 37.2% of people in the United States use medications that have an adverse effect of depression.

Abnormal Frontal Gyrus, Limbic Activity Observed During Attentional Activity in Pediatric Bipolar Disorder

Abnormal Frontal Gyrus, Limbic Activity Observed During Attentional Activity in Pediatric Bipolar Disorder

By

These results may be helpful in elucidating the specific brain mechanisms of bipolar disorder during cognitive development.

Loneliness, Low Social Support Associated With Poorer Mental Health Outcomes

Loneliness, Low Social Support Associated With Poorer Mental Health Outcomes

By

Preliminary generalizations point toward the potential therapeutic efficacy of targeting loneliness and social support for patients.

Belief That Abortion Harms Women's Mental Health Appears Misinformed

Belief That Abortion Harms Women's Mental Health Appears Misinformed

By

The notion that abortion harms women's mental health may be misinformed and should be re-examined according to scientific data such as these.

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

By

These data may lead to a more nuanced understanding of bipolar disorder and to a better definition of the effectiveness of interventions directed at treating both personality disorders and bipolar disorder.

Caffeine Sodium Benzoate Effective as Electroconvulsive Therapy Augmentation

Caffeine Sodium Benzoate Effective as Electroconvulsive Therapy Augmentation

By

This study was prompted by an ongoing shortage of injectable caffeine sodium benzoate in the United States from 2011 to 2017.

Sign Up for Free e-newsletters