Mood Disorders Archive
Socioeconomic status was the only environmental stressor that predicted an increase in SLC6A4 proximal promoter methylation.
A systematic review showed that most antidepressants are ineffective, and sometimes risky, for children and teens.
Polymorphisms of the GRIK4 gene modulate the response to electroconvulsive therapy.
Aversive conditioned stimulus-elicited habenula response decreased in individuals diagnosed with major depression.
Manipulating gene networks across distinct brain regions in mice affects susceptibility or resilience to depression-like behavior.
Age-dependent structural brain abnormalities identified in adolescents and adults with major depressive disorder.
A single session of whole-body hyperthermia treatment reduced depressive symptoms.
Patients with bipolar disorder taking lithium have lower rates of self-injury.
Study reports that most caregivers of ICU patients on ventilators describe high levels of depressive symptoms.
Research found increased incidence of mental health issues in young gay and bisexual men.
Those in the calorie cutting group said their sleep and relationships also improved.
Planned future studies will examine whether cervical inflammatory markers are associated with stress.
Clinicians should focus on treating patients' pain and psychological conditions together.
The trajectory of increasing depressive symptoms was associated with a higher risk of dementia.
At least 50% of patients who recover from an initial episode of major depressive disorder experience at least 1 subsequent episode.
Having more information on the long-term impact of antidepressants on weight could reduce the risk of weight-related morbidity for a large population of adults with depression.
Depression is one of many factors that can predict an inadequate treatment response in patients with episodic migraine.
How does a high carbohydrate or low carbohydrate weight loss diet affect depression in type 2 diabetes?
Research identifies high comorbidity rates between these 2 distinct diseases with underlying inflammation dysfunction.
Theory of Mind refers to the ability to assign mental states to oneself and others based on social cues such as tone of voice and facial expressions.
The risk of cardiovascular disease as a person's depression improves or worsens has largely remained unknown.
Research has found that patients with AS have an increased risk of developing certain depressive disorders following their diagnosis.
Oxytocin levels predicted the severity of postpartum depression symptoms among women with a history of depression.
Neither a specific antidepressant class nor individual drugs had any influence on the risk of stroke or transient ischemic attack over all of follow-up.
Although researchers are not certain about the mechanisms driving the link between depression and coffee or caffeine consumption, several potential explanations have emerged.
Treatment gives infusions of ketamine no more than once per week.
Modestly obese women who were educated were almost twice as likely to have depression than their normal-weight peers.
Study suggests statins may play a role in the development of new-onset depression.
Abnormal variations in the gene PDE10A19 might impact signaling of a messaging pathway responsible for learning, memory.
Feasible opportunities for healthy diet and activity linked to intentions, behaviors, and BMI.
Individuals with bipolar disorder or psychosis were 6 times more likely to die by suicide after prior self-harm.
Only 44% of pediatricians ask mothers during child visits about maternal depression.
Reductions in sweat-related health problems, anxiety and depression, symptom severity.
Results from a new survey suggest that significant gaps exist in the treatment for adults in the US with major depressive disorder.
New research suggests that a group of drugs being developed for mood disorders could also relieve chronic pain.
The odds ratios for children and adolescents were 2.39 for suicidality, 2.79 for aggression, and 2.15 for akathisia.
Risk up with exposure to serotonin-norepinephrine reuptake inhibitors in late pregnancy.
For adults, similar efficacy for cognitive behavioral therapy and antidepressants.
New research questions the efficacy of metyrapone as an adjunctive treatment for treatment-resistant depression.
Adults 65 years and older who had high levels of depression at least one time had a greater risk of experiencing heart disease or stroke.
Carbamazepine co-treatment linked to subtherapeutic anticoagulative effect of warfarin.
No significant risks were found in adults; the risk of suicidality and aggression doubled in children and teens.
Depressive symptoms have a gender-specific, cross-sectional association with CAC but no statistically significant associations with CAC progression.
In an update of their 2009 guidelines, the US Preventive Services Task Force has provided updated recommendations for screening for depression in adults.
Increased risk of any major congenital malformations, major cardiac malformations.
For every two years older women were at menopause, they had 2% reduced odds of later depression based on 13 of the studies.
Changes in IL-18 levels were more pronounced in depressed volunteers.
The activation of a brain pathway mimicked an antidepressant-like response to ketamine in mice.
NSI-189 has demonstrated the ability to produce new brain cells and has been effective in early stage trials.
In those suffering from clinical depression, two inflammatory markers, CRP and IL-6, were found to be elevated by up to 50%.
Significant association seen in SSRIs and venlafaxine in unipolar depression.
A team of researchers have linked a genetic variant of the SNX7 gene with both elevated levels of kynurenic acid and the disease symptoms of bipolar disorder.
An abandoned drug for stroke treatment may provide a safer treatment than lithium in treating bipolar disorder.
Women who took antidepressants during the second and/or third trimester were 87% more likely to have a child diagnosed with autism than those who did not take antidepressants during pregnancy.
There was no statistically significant differences in effectiveness between second-generation antidepressants and CBT for response or remission.
Almost 30% of medical residents reported having depression or depressive symptoms.
There was a significant difference in six proteins in those with bipolar I depression compared to the control group.
Depressed patients who took the SSRI escitalopram also saw declines in two neurotoxic compounds associated with inflammation.
The FDA's Psychopharmacologic Drugs Advisory Committee voted 9-4 that gepirone did not demonstrate substantial effectiveness.
Subjects with depression were 2.35 times more likely to be hospitalized for a preventable illness than those without depression.
After the addition of the black box warning on suicidality in 2004, clinicians were more likely to start adolescents on a lower SSRI dose.
The global market for anxiety treatments and antidepressants will decline at a compound annual growth rate of 1.25% between 2014 and 2020.
An FDA advisory committee is considering the fate of gepirone, which was rejected by the agency in 2002, 2004, and 2007.
Discrimination can create a cycle of depression and fewer prosocial behaviors.
Lower levels of certain omega-3 acids were associated with more bipolar symptoms, such as mania and suicidal ideation.
Loneliness can negatively impact cells of the immune system, making one more susceptible to physical illnesses.
Depressed patients with high levels of an inflammatory marker in their blood were particularly susceptible to anhedonia.
Bright light treatment, a standard therapy for SAD, may also be useful for nonseasonal depression.
The age difference between older mothers and daughters or older mothers' health problems may be to blame.
African-Americans who exhibit symptoms of major depression have twice the risk of stroke and coronary heart disease.
The researchers note the poor outcomes of online CBT were primarily from low engagement and low adherence to treatment.
Interns who participated in Web-based CBT were less likely to endorse suicidal ideation compared with those assigned to attention-control group.
Light therapy may be better when it comes to acute episodes of SAD, but CBT may be more effective to prevent relapse.
Studies have found only small improvements in treating depression with Omega-3s and have been of low-quality.
The APOE ε4 allele correctly predicted future depression, even after excluding people who later developed dementia.
Negative thoughts last longer in people with depression and interfere with their memory.
Patients who participated in CBT via the internet had equal or better outcomes compared with those who participated in traditional in-person CBT.
Early life stress in some people may alter the brain's ability to experience enthusiasm or pleasure.
Brain cells from lithium responder patients showed weakened excitability after being treated with lithium.
Once depressed patients who were symptom free didn't relapse for four times longer than those who had lingering symptoms.
Depression is a complex system of interacting symptoms, some of which may be far more important than others, researchers say.
Malfunctioning microglia can cause depression, but drugs that restore the normal functioning of them can be as effective as antidepressants.
While increasing antidepressant doses may not be wrong, there isn't evidence supporting that it increases effectiveness.
Eighty-six percent of teachers polled who said they felt burned out by their job met criteria for depression.
Study from the UK finds finds that 30% of pregnant women had five or more characteristics of depression.
85% of mental health apps recommended by the UK's National Health Service have no evidence that they work.
Smoking cessation demonstrated the strongest association with improving depression after heart attack.
Children on lithium showed much more significant improvement in their symptoms over the study period compared to placebo patients.
When people switch from female to male, their biology changes in a way that is consistent with a reduced risk for mood and anxiety disorders.
More than 50% of workers who said they were experiencing depressive symptoms said they didn't feel the need to seek help.
A substitution of substance misuse for food and increased stress may affect the likelihood of depression and suicidal behavior.
Patients who went on to have another episode of depression had a higher connectedness between two parts of the brain.
Siblings with positive relationships showed fewer risky behaviors, whereas siblings with negative relationships engaged in more risky behaviors.
Researchers discovered unpublished studies on psychotherapy that found the benefit of it not as great as thought.
Unique connectivity patterns identify potential depression switch in treatment-resistant depression.
The risk of depression was not different in patients with limited vs. extensive psoriasis.
How a patient being treated for depression responds to a placebo may determine how well they will respond to real antidepressant therapy.
A new study aims to determine whether a nasally administered version of the anesthetic esketamine can treat acutely suicidal patients.
44% of depressed participants who received the antipsychotic aripiprazole in addition to an antispychotic achieved remission.
The aim is to group patients based on comprehensive data profiles, rather than DSM criteria, which could improve treatment decisions.
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