Mood Disorder

Hormonal Contraception Associated With Depression

Hormonal Contraception Associated With Depression

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Researchers found that women who use hormonal contraception have an increased risk for first use of an antidepressant and first diagnosis of depression.

Does Methylphenidate Lead to Treatment-Emergent Mania?

Does Methylphenidate Lead to Treatment-Emergent Mania?

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Patients with comorbid bipolar disorder and ADHD may benefit from methylphenidate treatment, if it can be done without incurring the risk of mania.

Searching for Novel Endophenotypic Markers for Bipolar Disorder

Searching for Novel Endophenotypic Markers for Bipolar Disorder

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Intra-subject variability in reaction time (ISVRT) is viewed as a promising behavioral endophenotype for bipolar disorder.

Bipolar and Schizophrenia Disorders Accurately Predicted With WERCAP Sections

Bipolar and Schizophrenia Disorders Accurately Predicted With WERCAP Sections

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By using the Washington Early Recognition Center Affectivity and Psychosis (WERCAP) questionnaire, investigators accurately predicted bipolar disorder or schizophrenia in more than 85% of patients.

Sertraline Prevents Depression Following Traumatic Brain Injury

Sertraline Prevents Depression Following Traumatic Brain Injury

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Approximately 80% of depressive episodes have their onset during the first six months following traumatic brain injury.

Pupillometric Analysis For Assessment of Depression Recurrence

Pupillometric Analysis For Assessment of Depression Recurrence

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Pupillary reactivity to emotional stimuli has been investigated to provide objective information about the risk for recurrence of depressive symptoms in women.

Mood Disorders and the Disrupted Gut Microbial Milieu

Mood Disorders and the Disrupted Gut Microbial Milieu

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Lower diversity of microbial populations in the human gut has been identified in individuals with major depressive disorder.

Cohort Effect May Be Responsible For Increased Severity, Earlier Diagnoses in Bipolar Disorder

Cohort Effect May Be Responsible For Increased Severity, Earlier Diagnoses in Bipolar Disorder

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Findings suggest that in families with 2 generations of direct progenitors with bipolar disorder, an increase in bipolar disorder severity in future generations is likely.

Do Chronic Pain and RA Incite The Same Degree of Psychological Distress?

Do Chronic Pain and RA Incite The Same Degree of Psychological Distress?

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Researchers assessed pain, depression, anxiety, and stress in patients with chronic pain and rheumatoid arthritis.

Bipolar Disorder Treatment Initiated Early Found More Effective

Bipolar Disorder Treatment Initiated Early Found More Effective

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Treatment initiated in the early stages of bipolar disorder was found more effective than treatment in later stages.

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

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Dr. Roger McIntyre suggests that the clinical relevance of cognitive dysfunction for any individual patient can only be adjudicated on a case-by-case basis.

Whole Body Hyperthermia: The Future of Depression Treatment?

Whole Body Hyperthermia: The Future of Depression Treatment?

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Researchers investigated the lasting effects of whole body hyperthermia (WBH) in the first randomized, double-blind, [placebo]-controlled study of WBH for the treatment of MDD.

Does Impaired Cognition Precede Depression?

Does Impaired Cognition Precede Depression?

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Dysfunction across several cognitive domains is often concomitant with depression.

"Frequent Flyers" in Emergency Department More Likely to Have Depression

"Frequent Flyers" in Emergency Department More Likely to Have Depression

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"Detecting depression in the emergency department is of utmost importance," Dr. Brickman and colleagues wrote in their publication.

EEG Registry Reduces Trial-and-Error Approach to Depression Treatment

EEG Registry Reduces Trial-and-Error Approach to Depression Treatment

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The registry contains more than 10,000 EEGs and 38,000 pharmacological outcomes, and is accessible to clinicians worldwide.

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

Brain-derived Neurotrophic Factor and its Precursor proBDNF as Diagnostic Biomarkers for Mood Disorders

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mBDNF/proBDNF ratio could potentially serve as a novel biomarker for mood disorders.

Association Between Polymorphisms in the FKBP5 Gene and MDD

Association Between Polymorphisms in the FKBP5 Gene and MDD

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It is hypothesized that multiple single nucleotide polymorphisms (SNPs) work together to influence risk of complex neuropsychiatric disorders such as depression.

Treatment Rates Far from Meeting Increasing Global Burden of Bipolar Disorder

Treatment Rates Far from Meeting Increasing Global Burden of Bipolar Disorder

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Insights from the Global Burden of Disease Study 2013

Immune Biomarkers Identified in Patients With Bipolar Disorder During Manic Episodes

Immune Biomarkers Identified in Patients With Bipolar Disorder During Manic Episodes

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The immune system dysregulation may lead to or exacerbate neuropsychiatric conditions such as bipolar disorder.

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